Abstract
Objective
Evaluate the feasibility of local aortic distensibility measurement using central pressure estimation in the magnet, simultaneous to aortic imaging with cardiovascular magnetic resonance (CMR).
Methods
We studied 49 asymptomatic subjects (26 men, age 44±18 years). Ascending aortic strain was determined by CMR using automated segmentation of SSFP cine acquisitions. Central pressures were estimated as: 1) carotid pressures using tonometry measured immediately after CMR; 2) estimated from brachial cuff pressure using Vicorder™ acquired simultaneously with aortic cine imaging in the magnet. Central pressures were used to calculate aortic distensibility defined as aortic strain over central pulse pressure (AAD-carotid using carotid pressure and AAD-vicorder using Vicorder) and the carotid augmentation index (AIx). Carotid-femoral pulse wave velocity (cfPWV) was measured using tonometry.
Results
Average±SD systolic brachial, carotid and Vicorder pressures were respectively: 114±13, 105±13, 106±14mmHg. We found a strong linear relationship between AAD-carotid and AAD-vicorder (β=0.89, R2=0.91, p<0.001). The mean distensibility difference between the two methods was: −1.1±12 mmHg and variability 0.9%. Distensibilities measured using brachial pressures were higher than using either central pressures (Table).
The correlations with age, AIx and cfPWV obtained using AAD-vicorder (respectively: r=−0.82, r=−0.62; r=0.61; p<0.001) were significantly higher than using AAD-carotid (r=−0.79, r=−0.50, r=−0.58; p<0.001).
Conclusions
Aortic distensibility may be measured by CMR using central pressures measured in the magnet, simultaneously with cine acquisitions. Resulting distensibilities are closely related to those using carotid pressures measured by tonometry outside the magnet and achieve higher correlation with age and markers of global aortic stiffness such as AIx and cfPWV.
Article PDF
Author information
Authors and Affiliations
Rights and permissions
This is an open access article distributed under the CC BY-NC 4.0 license (http://creativecommons.org/licenses/by-nc/4.0/).
About this article
Cite this article
Redheuil, A., Bensalah, M., Kachenoura, N. et al. 12.01: Measuring Aortic Distensibility with CMR Using Central Pressures Estimated in the Magnet: Comparison with Carotid and Peripheral Pressures. Artery Res 5, 200 (2011). https://doi.org/10.1016/j.artres.2011.10.186
Published:
Issue Date:
DOI: https://doi.org/10.1016/j.artres.2011.10.186