Abstract
Primitive neuroectodermal tumor (PNET) is a rare and highly aggressive neoplasm that originates in neural crest neuroectodermal cells. It presents a bimodal distribution, which can affect both young and postmenopausal women. About 30% of patients present metastatic disease at the moment of diagnosis, and their survival in 2 years ranges from 25 to 60%. In this report, we describe the case of a 42-year-old patient with a history of vaginal bleeding and a growing tumor compromising the endometrium, initially diagnosed as an endometrial adenocarcinoma, which immunohistochemistry posteriorly revealed a PNET of the endometrium. She was treated with neoadjuvant chemotherapy but had an unfortunate evolution and died.
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Lins, R.S., Pereira, E.S., Romeiro, T.A. et al. Primitive Neuroectodermal Tumor (PNET) of the Endometrium. Indian J Gynecol Oncolog 17, 81 (2019). https://doi.org/10.1007/s40944-019-0325-y
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DOI: https://doi.org/10.1007/s40944-019-0325-y