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Raccomandazioni per l’utilizzo della diagnostica molecolare in Allergologia

Recommendations for the use of molecular diagnostics in the diagnosis of allergic diseases

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La Rivista Italiana della Medicina di Laboratorio - Italian Journal of Laboratory Medicine

An Erratum to this article was published on 02 December 2016

Riassunto

Il Gruppo di Studio in Allergologia della Società Italiana di Patologia Clinica e Medicina di Laboratorio (SIPMeL) propone alcune raccomandazioni di diagnostica di laboratorio delle malattie allergiche, basate sull’utilizzo di algoritmi diagnostici relativi all’impiego delle componenti allergeniche molecolari. Lo scopo è fornire ai patologi e ai clinici informazioni che consentano un utilizzo appropriato di questa diagnostica, che può essere ragionevolmente considerata di secondo livello e che, a fronte di un maggiore impegno economico, per il quale deve esserne assolutamente evitato l’impiego indiscriminato, permette di delineare il corretto profilo di sensibilizzazione del paziente allergico.

Il percorso metodologico seguito è costituito da una fase iniziale di discussione fra tutti i componenti del Gruppo di Studio per integrare le conoscenze derivate dalle evidenze scientifiche, dalla revisione da parte di esperti italiani e stranieri e dalla successiva produzione del presente documento da diffondere a tutti coloro che si occupano di diagnostica allergologica.

Summary

The Study Group on Allergology of the Italian Society of Clinical Pathology and Laboratory Medicine (SIPMeL) developed recommendations on the diagnosis of allergic diseases based on the use of molecular allergenic components. The purpose of this document is to provide the pathologists and the clinicians with information and algorithms enabling a proper use of this second-level diagnostics. In the face of greater economic commitments, for which its indiscriminate use must be absolutely avoided, molecular diagnostics allows definition of the exact sensitization profile of the allergic patient.

The methodology followed to develop these recommendations included an initial phase of discussion between all the components of the Study Group to integrate the knowledge derived from scientific evidence, a revision of the recommendations made by Italian and foreign experts, and the subsequent production of this document to be disseminated to all those who deal with allergy diagnostics.

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Authors and Affiliations

  1. Allergologia e Immunologia Clinica, Ospedale “S. Maria degli Angeli”, Pordenone, Italia

    Danilo Villalta

  2. Immunopatologia e Allergologia, Azienda Sanitaria Universitaria Integrata, Udine, Italia

    Elio Tonutti

  3. Laboratorio di Patologia Clinica, Ospedale San Antonio, Tolmezzo, UD, Italia

    Nicola Bizzaro

  4. Laboratorio Analisi, Ospedale “Buccheri-La Ferla”, Palermo, Italia

    Ignazio Brusca

  5. Laboratorio Analisi, P.T.P, Nuovo Regina Margherita, Roma, Italia

    Vittorio Sargentini

Authors
  1. Danilo Villalta
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  2. Elio Tonutti
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  3. Nicola Bizzaro
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  4. Ignazio Brusca
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  5. Vittorio Sargentini
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Correspondence to Danilo Villalta.

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Additional information

Per il Gruppo di Studio in Allergologia della Società Italiana di Patologia Clinica e Medicina di Laboratorio (GdS-ALL SIPMeL)

An erratum to this article is available at http://dx.doi.org/10.1007/s13631-016-0137-3.

Appendice

Appendice

Hanno collaborato alla realizzazione di questo documento, partecipando alla revisione del lavoro, i seguenti componenti del Gruppo di Studio di Allergologia della Società Italiana di Patologia Clinica e Medicina di Laboratorio:

  1. (1)

    Agostini Pierfrancesco, Patologia Clinica e Laboratorio Analisi, Ospedale don Tonino Bello, Molfetta (BA)

  2. (2)

    Antico Antonio, Laboratorio Analisi, ULSS 4, Santorso (VI)

  3. (3)

    Bagnasco Marcello, DIMI, Università di Genova, Genova

  4. (4)

    Bonaguri Chiara, Laboratorio diagnostica ematochimica, Azienda Ospedaliero-Universitaria, Parma

  5. (5)

    Caponi Laura, U.O. Laboratorio Analisi Specializzate Azienda Ospedaliero-Universitaria pisana

  6. (6)

    Caruso Beatrice, Laboratorio Analisi Chimico Cliniche ed Ematologiche Azienda Ospedaliera di Verona

  7. (7)

    Deleonardi Gaia, Laboratorio Analisi, Ospedale Maggiore, Bologna

  8. (8)

    Milanesi Bruno, Patologia clinica, Desenzano del Garda (BS)

  9. (9)

    Musso Maura Fabrizia, Laboratorio Analisi, Azienda Ospedaliera, Santa Croce, Cuneo

  10. (10)

    Platzgummer Stefan, Laboratorio centrale, Ospedale Civile di Merano (BZ)

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Villalta, D., Tonutti, E., Bizzaro, N. et al. Raccomandazioni per l’utilizzo della diagnostica molecolare in Allergologia. Riv Ital Med Lab 12, 198–215 (2016). https://doi.org/10.1007/s13631-016-0122-x

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