Abstract
This case series reported on five patients with radiation-recurrent localized prostate cancer (PCa) who underwent salvage robot-assisted radical prostatectomy (sRARP). Median postoperative follow-up period was 8 months. Median (range) peri-operative parameters such as operative time, the estimated blood loss, and length of hospital stay were 127 min (113–158), 61 ml (54–111), and 9 days (8–11), respectively. None of the five patients required conversion to an open approach or required a blood transfusion, or experienced a rectal/ureteral injury. Urinary leakage was present in one patient (20%) at the initial cystogram. Transurethral electrocoagulation under spinal anesthesia was required to control hematuria in one patient (20%). Two patients (40%) experienced biochemical progression; no patient died from PCa or other causes during the follow-up period. Of five patients, three (60%) were continent. For patients with radiation-recurrent localized PCa, sRARP might become a feasible surgical option with acceptable outcomes.
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Abbreviations
- ADT :
-
Androgen deprivation therapy
- ASA-PS :
-
American Society of Anesthesiologists Physical Status
- BMI :
-
Body mass index
- CAB :
-
Combined androgen blockade
- CCI :
-
Charlson Comorbidity Index
- CDC :
-
Clavien–Dindo Classification
- EAU :
-
European Association of Urology
- EBL :
-
Estimated blood loss
- ECOG-PS :
-
Eastern Cooperative Oncology Group Performance Status
- ENZA :
-
Enzalutamide
- EPE :
-
Extraprostatic extension
- G/S :
-
Gleason score
- HBOT :
-
Hyperbaric oxygen therapy
- IMRT:
-
Intensity-modulated radiation therapy
- IPSS :
-
International Prostate Symptom Score
- N/A :
-
Not available
- ORP :
-
Open radical prostatectomy
- PBT :
-
Proton beam therapy
- PCa :
-
Prostate cancer
- PLND :
-
Pelvic lymph node dissection
- PSA :
-
Prostate-specific antigen
- PSMA-PET :
-
Prostate-specific membrane antigen imaging using positron emission tomography
- RM :
-
Radial margin
- RT :
-
Radiation therapy
- sRARP :
-
Salvage robot-assisted radical prostatectomy
- sRP :
-
Salvage radical prostatectomy
- TNM :
-
Tumor node metastasis classification
- TUC :
-
Transurethral electrocoagulation
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SY took the lead in writing the manuscript. YN aided in interpreting the results and worked on the manuscript. All authors provided critical feedback and helped shape the research, analysis, and manuscript.
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Yajima, S., Nakanishi, Y., Umino, Y. et al. Salvage Robot-Assisted Radical Prostatectomy (sRARP) for Radiation-Recurrent Prostate Cancer: a Single-Center Experience. Indian J Surg Oncol 14, 361–365 (2023). https://doi.org/10.1007/s13193-022-01671-y
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DOI: https://doi.org/10.1007/s13193-022-01671-y