Abstract
The attachment of the palatopharyngeus extended from the posterior end of the thyroid cartilage to the posterior margin of the inferior constrictor attachment that might contribute to successive swallowing movements. Laryngeal elevation is essential for proper swallowing and breathing. Recently, clinical research has demonstrated that the palatopharyngeus, a longitudinal muscle of the pharynx, is involved in the elevation of the larynx. However, the morphological relationship between the larynx and palatopharyngeus remains unclear. In the present study, we analyzed the attachment site and characteristics of the palatopharyngeus in the thyroid cartilage. We evaluated 14 halves of seven heads from Japanese cadavers (average age: 76.4 years); 12 halves, anatomically and two halves histologically. A part of the palatopharyngeus, which originated from the inferior aspect of the palatine aponeurosis, was attached to the inner and outer surfaces of the thyroid cartilage through collagen fibers. The attachment area extends from the posterior end of the thyroid cartilage to the posterior margin of the attachment site of the inferior constrictor. The palatopharyngeus may elevate the larynx with the suprahyoid muscles and contribute to successive movements of swallowing with surrounding muscles. Based on our findings and previous studies, palatopharyngeus with various muscle bundle directions may be essential for the coordination of continuous swallowing events.
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The datasets used and analyzed during the current study are available from the corresponding author upon reasonable request.
References
Bingjie L, Tong Z, **nting S, Jianmin X, Guijun J (2010) Quantitative videofluoroscopic analysis of penetration-aspiration in post-stroke patients. Neurol India 58(1):42–47. https://doi.org/10.4103/0028-3886.60395
Choi DY, Bae JH, Youn KH, Kim HJ, Hu KS (2014) Anatomical considerations of the longitudinal pharyngeal muscles in relation to their function on the internal surface of pharynx. Dysphagia 29(6):722–730. https://doi.org/10.1007/s00455-014-9568-z
Fukino K, Tsutsumi M, Sanudo J, Ono T, Akita K (2019) Anatomical significance of the spatial distribution of the palatopharyngeus with regard to velopharyngeal closure. Cleft Palate-Craniofacial J 56(6):744–750. https://doi.org/10.1177/1055665618813082
Fukino K, Tsutsumi M, Nimura A, Miwa K, Ono T, Akita K (2021) Anatomy of inferior end of palatopharyngeus: its contribution to upper esophageal sphincter opening. Eur Arch Oto-Rhino-Laryngol 278(3):749–754. https://doi.org/10.1007/s00405-020-06437-2
Gawryszuk A, Bijl HP, Holwerda M, Halmos GB, Wedman J, Witjes MJH, van der Vliet AM, Dorgelo B, Langendijk JA (2019) Functional Swallowing Units (FSUs) as organs-at-risk for radiotherapy. PART 1: Physiology and anatomy. Radiotherapy Oncol 130:62–67. https://doi.org/10.1016/j.radonc.2018.10.028
Henle J (1873) Handbuch der eingeweidelehre des Menschen (2. Aufl. ed. Vol. 2. Bd.): Vieweg
Hoekema A, Hovinga B, Stegenga B, De Bont LG (2003) Craniofacial morphology and obstructive sleep apnoea: a cephalometric analysis. J Oral Rehabil 30(7):690–696. https://doi.org/10.1046/j.1365-2842.2003.01130.x
Huang YL, Hsieh SF, Chang YC, Chen HC, Wang TG (2009) Ultrasonographic evaluation of hyoid-larynx approximation in dysphagic stroke patients. Ultrasound Med Biol 35(7):1103–1108. https://doi.org/10.1016/j.ultrasmedbio.2009.02.006
Iwanaga J, Singh V, Ohtsuka A, Hwang Y, Kim HJ, Morys J, Ravi KS, Ribatti D, Tranior PA, Sañudo JR, Apaydin N, Şengül G, Albertine KH, Walocha JA, Loukas M, Duparc F, Paulsen F, Sol MD, Adds P, Tubbs RS (2021) Acknowledging the use of human cadaveric tissues in research papers: Recommendations from anatomical journal editors. Clin Anatomy 34(1):2–4
Meng H, Murakami G, Suzuki D, Miyamoto S (2008) Anatomical variations in stylopharyngeus muscle insertions suggest interindividual and left/right differences in pharyngeal clearance function of elderly patients: a cadaveric study. Dysphagia 23(3):251–257. https://doi.org/10.1007/s00455-007-9131-2
Okuda S, Abe S, Kim HJ, Agematsu H, Mitarashi S, Tamatsu Y, Ide Y (2008) Morphologic characteristics of palatopharyngeal muscle. Dysphagia 23(3):258–266. https://doi.org/10.1007/s00455-007-9133-0
Pearson WG Jr, Langmore SE, Yu LB, Zumwalt AC (2012) Structural analysis of muscles elevating the hyolaryngeal complex. Dysphagia 27(4):445–451. https://doi.org/10.1007/s00455-011-9392-7
Pearson WG Jr, Hindson DF, Langmore SE, Zumwalt AC (2013) Evaluating swallowing muscles essential for hyolaryngeal elevation by using muscle functional magnetic resonance imaging. Int J Radiat Oncol Biol Phys 85(3):735–740. https://doi.org/10.1016/j.ijrobp.2012.07.2370
Plank J, Rychlo A (1952) [A method for quick decalcification]. Zentralblatt fur allgemeine Pathologie u. Pathologische Anatomie 89(8):252–254
Sakamoto Y (2015) Spatial relationship between the palatopharyngeus and the superior constrictor of the pharynx. Surg Radiol Anat 37(6):649–655. https://doi.org/10.1007/s00276-015-1444-5
Sivarao DV, Goyal RK (2000) Functional anatomy and physiology of the upper esophageal sphincter. Am J Med 108(Suppl 4a):27S-37S. https://doi.org/10.1016/s0002-9343(99)00337-x
Stephan M (2015) Gray's anatomy. In: S. S (Ed.), Pharynx, vol 41. Elsevier Amsterdam, The Netherlands, pp 571–585
von Luschka H (1868) Der Schlundkopf des Menschen: Laupp.
Yamashiro Y, Kryger M (2012) Is laryngeal descent associated with increased risk for obstructive sleep apnea? Chest 141(6):1407–1413. https://doi.org/10.1378/chest.10-3238
Zhang J, Zhou Y, Wei N, Yang B, Wang A, Zhou H, Zhao X, Wang Y, Liu L, Ouyoung M, Villegas B, Groher M (2016) Laryngeal elevation velocity and aspiration in acute ischemic stroke patients. PloS one 11(9):e0162257. https://doi.org/10.1371/journal.pone.0162257
Acknowledgements
The authors sincerely thank those who donated their bodies to science so that anatomical research could be performed. Results from such research can potentially increase mankind’s overall knowledge that can then improve patient care. Therefore, these donors and their families deserve our highest gratitude. We would like to thank Editage (www.editage.jp) for English language editing.
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Fukino, K., Iida, K., Tsutsumi, M. et al. Evaluation of morphological features of palatopharyngeus insertion into the thyroid cartilage. Anat Sci Int 98, 448–453 (2023). https://doi.org/10.1007/s12565-023-00709-7
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DOI: https://doi.org/10.1007/s12565-023-00709-7