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Entwicklung komplexer Screening verfahren am Beispiel von Hsp90

  • Wissenschaft · Special: Laborautomation
  • Target-Omics
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Abstract

The protein target-microarray assay is a hitherto underestimated method in the investigation of protein-ligand/inhibitor and protein-protein/inhibitor-interactions. It is a versatile and adaptable method that can also be used in the diagnostic and individual medicine. Following, examples for target-oriented tests with high potential for development are demonstrated.

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Author information

Authors and Affiliations

  1. Biomolekulares Wirkstoffzentrum (BMWZ), Universität Hannover, Hannover, Deutschland

    Sabine Helmsen, Christin Ahlbrecht, Vjaceslavics Hrupins & Carsten Zeilinger

  2. Institut für Technische Chemie, Leibniz Universität Hannover, Callinstraße 5, D-30167, Hannover, Deutschland

    Frank Stahl

Authors
  1. Sabine Helmsen
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  2. Christin Ahlbrecht
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  3. Vjaceslavics Hrupins
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  4. Frank Stahl
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  5. Carsten Zeilinger
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Corresponding author

Correspondence to Frank Stahl.

Additional information

Sabine Helmsen 2016 Bachelorabschluss in Chemie an der Universität Hannover. Derzeit Masterarbeit am Biomolekularen Wirkstoffzentrum (BMWZ) über Proteinmikroarrays, Masterstudiengang Analytik.

Vjaceslavs Hrupins 2011–2014 Bachelorstudium Biochemie und 2014–2016 Masterstudium Wirk- und Naturstoffchemie an der Universität Hannover. Master arbeit am Biomolekularen Wirkstoffzentrum (BMWZ) über Proteinmikroarrays. Zurzeit Promotion bei Prof. Dr. R. J. Cox.

Christin Ahlbrecht 2011–2017 Studium Life Science an der Universität Hannover. Masterarbeit am Biomolekularen Wirkstoffzentrum (BMWZ) über Proteinmikro arrays. Zurzeit Promotion bei Prof. Dr. O. Plettenburg.

Frank Stahl Biologiestudium an der Universität Gießen, dort 1998 Promotion bei Prof. Dr. A. **oud am Institut für Biochemie. Postdoc an der Gesellschaft für Biotechnologische Forschung mbh (GBF), Braunschweig. Danach Labormanager, Genedrugs GmbH, Hechingen. Seit 2003 Arbeitsgruppenleiter Chiptechnologien am Institut für Technische Chemie der Universität Hannover.

Carsten Zeilinger Biologiestudium an der Universität Osnabrück, dort 1990 Promotion bei Prof. Dr. E. W. Weiler am Lehrstuhl Pflanzenphysiologie. 1998 Habilitation in Pflanzenphysiologie an der Universität Hannover. Seit 2008 Arbeitsgruppenleiter am Biomolekularen Wirkstoffzentrum (BMWZ), Hannover.

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Helmsen, S., Ahlbrecht, C., Hrupins, V. et al. Entwicklung komplexer Screening verfahren am Beispiel von Hsp90. Biospektrum 23, 540–543 (2017). https://doi.org/10.1007/s12268-017-0839-8

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  • DOI: https://doi.org/10.1007/s12268-017-0839-8

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