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Incidence and management of mycobacterial infection in solid organ transplant recipients

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Abstract

Although advances in surgical technique, immunosuppressive regimens, and medical management have led to improved survival and quality of life after solid organ transplantation, infection continues to represent a major cause of morbidity and mortality in transplant recipients. Immunosuppressive therapy after transplantation compromises cell-mediated immunity in particular, leaving the patient at risk for opportunistic as well as routine community-acquired infections. Mycobacterial infection is a rare but important complication of solid organ transplantation, presenting significant risk to the patient and challenges in terms of treatment. The available literature consists predominantly of case reports and institutional experiences. This article examines both Mycobacterium tuberculosis and nontuberculous mycobacterial infection in the transplant setting.

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Authors and Affiliations

  1. Pulmonary, Allergy and Critical Care Division, University of Pennsylvania Medical Center, 835 West Gates Building, 3600 Spruce Street, Philadelphia, PA, 19104, USA

    Ming-Hui Fan

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  1. Ming-Hui Fan
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  2. Denis Hadjiliadis
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Correspondence to Ming-Hui Fan.

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Fan, MH., Hadjiliadis, D. Incidence and management of mycobacterial infection in solid organ transplant recipients. Curr Infect Dis Rep 11, 216–222 (2009). https://doi.org/10.1007/s11908-009-0032-4

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