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Coronary CT Angiography Using Low Iodine Delivery Rate and Tube Voltage Determined by Body Mass Index: Superiority in Clinical Practice

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Summary

To explore the feasibility and superiority of iodine delivery rate (IDR) and tube voltage determined by patients’ body mass index (BMI) in coronary CT angiography (CCTA), a total of 1567 patients undertaking CCTA during Feb. and Dec. 2016 were enrolled and divided into two groups. In the control group, the IDR and tube voltage were fixed, while in the experimental group, the IDR and tube voltage were determined by patients’ BMI. The volume of iodinated contrast media (ICM), extravasation rate, extravasation volume, extravasation recovery interval, incidence rate of adverse reactions, effective dose (ED) and image quality of the two groups were compared. The experiments demonstrated that the ICM volume, extravasation rate, extravasation volume, extravasation recovery interval, incidence of adverse reactions and ED were lower or shorter in the experimental group than in the control group, and the differences were statistically significant (all P<0.05). However, there were no significant differences in the mean CT value, image noise, signal to noise ratio and contrast to noise ratio between the two groups (all P<0.05), which were consistent with the diagnosticians’ subjective evaluation outcomes. Our findings suggested that in CCTA, it is feasible to determine the IDR and tube voltage based on patients’ BMI; low tube voltage and IDR are superior to the fixed tube voltage and IDR and are worthy of clinical promotion.

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Authors and Affiliations

  1. Department of Diagnostic Radiology, the First Hospital of Medical Science Centre, **’an Jiaotong University, **’an, 710061, China

    Wang Yuan, Ting-ting Qu, Mei-yu Wang, Yuan Qu, Gang Niu & Jian Yang

  2. Department of Dermatology, the Ninth Hospital of **’an, **’an, 710054, China

    Hui-juan Wang

Authors
  1. Wang Yuan
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  2. Ting-ting Qu
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  3. Hui-juan Wang
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  4. Mei-yu Wang
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  5. Yuan Qu
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  6. Gang Niu
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  7. Jian Yang
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Correspondence to Jian Yang.

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Conflict of Interest Statement

The authors declare no competing financial interests.

This project was supported by the New Century Excellent Talent Support Plan of the Ministry of Education, China (No. NCET-11-0438).

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Yuan, W., Qu, Tt., Wang, Hj. et al. Coronary CT Angiography Using Low Iodine Delivery Rate and Tube Voltage Determined by Body Mass Index: Superiority in Clinical Practice. CURR MED SCI 39, 825–830 (2019). https://doi.org/10.1007/s11596-019-2112-5

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  • DOI: https://doi.org/10.1007/s11596-019-2112-5

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