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Catalytic removal of tert-butyldimethylsilyl (TBS) and tetrahydropyranyl (THP) groups from protected alcohols by NO+BF4 − in methanol

  • Letter
  • Organic Chemistry
  • Published:
Chinese Science Bulletin

Abstract

An effective, catalytic method has been developed to remove TBS and THP groups from protected alcohols. TBS and THP ethers were selectively cleaved using a catalytic amount of NO+BF4 − (5 mol%) in methanol at room temperature.

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Authors and Affiliations

  1. State Key Laboratory of Applied Organic Chemistry, Lanzhou University, Lanzhou, 730000, China

    JianTao Wang, WenTao Wu, YanFen Xu & LongMin Wu

Authors
  1. JianTao Wang
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  2. WenTao Wu
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  3. YanFen Xu
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  4. LongMin Wu
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Corresponding author

Correspondence to LongMin Wu.

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Cite this article

Wang, J., Wu, W., Xu, Y. et al. Catalytic removal of tert-butyldimethylsilyl (TBS) and tetrahydropyranyl (THP) groups from protected alcohols by NO+BF4 − in methanol. Chin. Sci. Bull. 55, 2803–2806 (2010). https://doi.org/10.1007/s11434-010-3130-7

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  • DOI: https://doi.org/10.1007/s11434-010-3130-7

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