Abstract
Application of medicinal plant to cure ailments has been practiced by several civilizations. Nowadays, contamination of heavy metals and pesticide residues in medicinal plant is a serious concern, due to toxic effects on human health. The present study was designed with an aim to quantify the heavy metals and pesticide residues in the 20 medicinal herbs, frequently sold in the local market as raw material without any quality assurance. The concentrations of the elements are as follows: copper (2.42–19.14 μgg−1), cadmium (0.01–2.10 μgg−1), chromium (17.63–58.63 μgg−1), iron (7.61–322.6 μgg−1), and lead (13.00–54.47 μgg−1), whereas total metal concentration ranged between 44.73 and 385.15 μgg−1. Among the organic pesticides, HCH (1.63–6.44 μgg−1) and DDT (0.63–7.14 μgg−1) isomers were found to be present in medicinal plant material. Result showed that lead and chromium concentrations in the herbs were above the permissible limits set by WHO. These herbs should be regularly checked for quality assurance before using raw or as a herbal formulation to avoid chronic exposure of metal and pesticides to human being.
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Anna F, Marzanna K, Edward S (2015) Determination of toxic metals by ICP-MS in Asiatic and European medicinal plants and dietary supplements. J Trace Elem Med Biol 30:54–58
Arpadjan S, Celik G, Taskesen S, Gucen S (2008) Arsenic, cadmium and lead in medicinal herbs and their fractionation. Food Chem Toxicol 46:2871–2875
Bodeker C, Bodeker G, Ong CK, Grundy CK, Burford G, Shein K (2005) WHO global atlas of traditional, complementary and alternative medicine. World Health Organization, Geneva
Chauhan R, Awasthi S, Singh AP, Srivastava S, Pande V, Tripathi RD, Kumar A (2017) Heavy metal tolerance in crop plants: physiological and biochemical aspect. In: Shukla V et al (eds) Plant adaptation strategies in changing environment. Springer Nature, Singapore, pp 253–268. https://doi.org/10.1007/978-981-10-6744-0_11
Dimitrova Z (1999) The history of pharmacy. St Clement of Ohrid, Sofija, pp 13–26
Duruibe JO, Ogwuegbu MOC, Egwurugwu JN (2007) Heavy metal pollution and human biotoxic effects. Int J Physical Sci 2(5):112–118
Govindaraghvan S, Nikolaus JS (2015) Quality assessment of medicinal herbs and their extracts: Criteria and prerequisites for consistent safety and efficacy of herbal medicines. Epilepsy Behav 52:363–371
Haider S, Naithani V, Barthwal J, Kakkar P (2004) Heavy metal content in some therapeutically important medicinal plants. Bull Environ ContamToxicol 72:119–127
Hellawell JM (1988) Toxic substances in river and streams. Environ Pollut 50:61–85
Khan CS, Cao Q, Zheng YM, Huang YZ, Zhu YG (2008) Health risks of heavy metals in contaminated soils and food crops irrigated with wastewater in Bei**g, China. Environ Pollut 152(3):686–692
Khatoon H, Pant A, Rai JPN (2017) Plant adaptation to recalcitrant chemicals. In: Shukla V et al (eds) Plant adaptation strategies in changing environment. Springer Nature, Singapore, pp 269–290. https://doi.org/10.1007/978-981-10-6744-0_11
Kishan PS, Bhattacharya S, Sharma P (2014) American-Eurasian assessment of heavy metal contents of some Indian medicinal plants. J Agric Environ Sci 14(10):1125–1129
Kumar N, Kumar S, Bauddh K, Dwivedi N, Shukla P, Singh DP, Barman SC (2015) Toxicity assessment and accumulation of metals in radish irrigated with battery manufacturing industry effluent. Int J Veg Sci 00:1–13
Kumar D, Bharti SK, Anand S, Kumar N (2018) Bioaccumulation and biochemical responses of Vetiveria zizanioides grown under cadmium and copper stresses. Environ Sustain 1:133–139. https://doi.org/10.1007/s42398-018-0009-z
Kunle OF, Egharevba HO, Ahmadu PO (2012) Standardization of herbal medicines: a review. Int J Biodivers Conserv 4(3):101–112
Lasat MM, Fuhrman M, Ebbs SD, Cornish JE, Kochian LV (1998) Phytoremediation of radiocesium-contaminated soil: evaluation of cesium-137 bioaccumulation in the shoots of three plant species. J Environ Qual 27(1):165–169
McLachlan MS, Horstmann M (1998) Forests as filters of airborne organic pollutants. Environ Sci Technol 32:413–420
Mishra C, Sharma S, Kakkar P (2007) A study to evaluate heavy metals and organochlorine pesticide residue in Zingiber officinalerosc. collected from different ecological zones of India. Bull Environ Contam Toxicol 79:95–98
Neha KD, ShuklaP KS, Bauddh K, Tiwari J, Dwivedi N, Barman SC, Singh DP, Kumar N (2017) Metal distribution in the sediments, water and naturally occurring macrophytes in the river Gomti, Lucknow, Uttar Pradesh, India. Curr Sci 113(8):1578–1585
Olowoyo JO, Okedeyi OO, Mkolo NM, Lion GN, Mdakane STR (2012) Uptake and translocation of heavy metals by medicinal plants growing around a waste dump site in Pretoria, South Africa. South Afr J Bot 78:116–121
Orisakwe OE, Nduka JK, Amadi CN, Dike D, Obialor OO (2012) Evaluation of potential dietary toxicity of heavy metals of vegetables. J Environ Anal Toxicol 2(3):136–139
Ouyang Y (2002) Phytoremediation of modeling plant uptake and contaminant transport in the soil plant atmosphere continuum. J Hydrol 266(1–2):66–82
Petrovska BB (2012) Historical review of medicinal plants’ usage. Pharmacogn Rev 6(11):1–5
Reinholds I, Pugajeva I, Bavrins K, Kuckovska G, Bartkevics V (2017) Mycotoxins, pesticides and toxic metals in commercial spices and herbs. Food Addit Contam Part B 10(1):5–14
Rodriguesa AAZ, De Queiroz MELR, De Oliveira AF, Heleno AAFF, Zambolim L, Freitasa JF, Morais EHC (2017) Pesticide residue removal in classic domestic processing of tomato and its effects on product quality J Environ Sci Health Part B :1–8
Shaban NS, Abdou KA, Hassan NEY (2016) Impact of toxic heavy metals and pesticideresidues in herbal products. Beni-Suef Uni J Basic Appl Sci 5:102–106
Srivastava SK, Rai V, Srivastava M, Rawat AKS, Mehrotra S (2006a) Stimation of heavy metals in different Berberis species and its market samples. Environ Monit Assess 16(1–3):315–320
Srivastava LP, Kumar N, Gupta KP, Raizada RB (2006b) Status of HCH residues in Indian medicinal plant materials. Bull Environ Contam Toxicol 76:782–790
Srogi K, Włochowicz A, Szczepanik K (2002) Determination of heavy metal contents in samples of medicinal herbs. Pol J Environ Stud 11(5):467–471
Verma P, George KV, Singh HV, Singh RN (2007) Modeling cadmium accumulation in radish, carrot, spinach and cabbage. Appl Math Model 31(8):1652–1661
Wiart C (2006) Etnopharmacology of medicinal plants. Humana Press, New Jersey, pp 1–50
World Health Organization (2007) WHO guidelines for assessing quality of herbal medicines quality of herbal medicines with reference to contaminants and residues. Geneva
Ziarati P (2012) Determination of some heavy metals in popular medicinal plants of Tehran’s market. J Pharma Health Sci 1(3):31–36
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The authors would like to thank The Head, Department of Environmental Science, BBAU, Lucknow, India, for providing infrastructural support.
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Kumar, N., Kulsoom, M., Shukla, V. et al. Profiling of heavy metal and pesticide residues in medicinal plants. Environ Sci Pollut Res 25, 29505–29510 (2018). https://doi.org/10.1007/s11356-018-2993-z
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DOI: https://doi.org/10.1007/s11356-018-2993-z