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Catheter ablation for atrial fibrillation in patients with the Marfan and Marfan-like syndromes

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Abstract

Patients with the Marfan syndrome may pose a difficult challenge for catheter-based interventions due to frequent coexisting valve disease, potential delay in vascular healing and repair, and intra-atrial scar from prior cardiac surgery. We report a case series of four patients with Marfan or Marfan-like syndromes who underwent ablation for drug-refractory atrial fibrillation. Ultimately three of four patients remained in sinus rhythm, however most patients required multiple ablative attempts and long-term atrial flutter was common. Nonetheless, peri-procedural complications were minimal despite the connective tissue disorder and prosthetic valves in three of four patients. In conclusion, catheter ablation of AF in patients with Marfan syndrome is a viable option in those individuals refractory to conventional therapy.

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Authors and Affiliations

  1. Division of Cardiovascular Disease, Department of Internal Medicine, Mayo Clinic, Rochester, MN, USA

    T. Jared Bunch, Heidi M. Connolly, Samuel J. Asirvatham, Peter A. Brady, Bernard J. Gersh, Thomas M. Munger, Win-Kuang Shen, Kristi H. Monahan & Douglas L. Packer

  2. Heart Rhythm Services, Mayo Clinic, 200 First St. SW, Rochester, MN, 55902, USA

    T. Jared Bunch

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  1. T. Jared Bunch
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  2. Heidi M. Connolly
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  3. Samuel J. Asirvatham
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  4. Peter A. Brady
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  5. Bernard J. Gersh
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  6. Thomas M. Munger
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  7. Win-Kuang Shen
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  8. Kristi H. Monahan
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  9. Douglas L. Packer
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Correspondence to T. Jared Bunch.

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Bunch, T.J., Connolly, H.M., Asirvatham, S.J. et al. Catheter ablation for atrial fibrillation in patients with the Marfan and Marfan-like syndromes. J Interv Card Electrophysiol 20, 15–20 (2007). https://doi.org/10.1007/s10840-007-9162-5

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  • DOI: https://doi.org/10.1007/s10840-007-9162-5

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