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The rate of endophthalmitis after pars plana vitrectomy and its risk factors

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Abstract

Purpose

To study the incidence of endophthalmitis after pars plana vitrectomy, its causative organisms, and visual acuity outcomes.

Patients and methods

In this retrospective, comparative study, the medical records of patients with acute-onset postoperative endophthalmitis after pars plana vitrectomy at Farabi Eye Hospital, Tehran, Iran, during a 12-year period between January 2004 and November 2015 were reviewed. To compare the endophthalmitis patients with other cases who underwent pars plana vitrectomy at the same day and also the same operating room, a control group was developed by gathering the data from surgical records.

Results

In the present study, the incidence rate of pos- vitrectomy endophthalmitis was 0.04% (16/39783). The organisms identified in aqueous or vitreous cultures (culture positive 44%) included Streptococcus pneumoniae (two patients, 12.5%), Pseudomonas aeruginosa (two patients, 12.5%), fungi (two patients, 12.5%), and Streptococcus viridans (one patient, 6.25%). Visual acuity after treatment for endophthalmitis ranged from light perception (7 eyes) to hand motion (1 eye), and evisceration was performed in 8 eyes (50%). When comparing the cases (patients develo** endophthalmitis) and controls (patients with no complications operated in the same day and place of operation with the case group), only not using tamponade showed a statistically significant relation with the occurrence of endophthalmitis (p = 0.034).

Conclusion

Our results indicated low incidence of endophthalmitis after pars plana vitrectomy comparable to previous studies which resulted in poor visual acuity. It seems that not using tamponade might increase the risk of endophthalmitis among these patients.

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Acknowledgements

We want to thank Ms. Shadi Rezaei for her help in gathering data for this project.

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Authors and Affiliations

  1. Eye Research Center, Farabi Eye Hospital, Tehran University of Medical Sciences, Tehran, Iran

    Seyed Ali Tabatabaei, Mohammad Soleimani, Hadi Vakili, Morteza Naderan, Alireza Lashay & Houshang Faghihi

  2. Tehran University of Medical Sciences, Tehran, Iran

    Mehdi Yaseri

Authors
  1. Seyed Ali Tabatabaei
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  2. Mohammad Soleimani
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  4. Morteza Naderan
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Corresponding author

Correspondence to Mohammad Soleimani.

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Conflict of interest

All authors certify that they have no affiliations with or involvement in any organization or entity with any financial interest (such as honoraria; educational grants; participation in speakers’ bureaus; membership, employment, consultancies, stock ownership, or other equity interest; and expert testimony or patent-licensing arrangements), or non-financial interest (such as personal or professional relationships, affiliations, knowledge, or beliefs) in the subject matter or materials discussed in this manuscript.

Ethical approval

All procedures performed in our study were in accordance with the ethical standards of the institutional and/or national research committee (ethics committee of Shahid Beheshti University of Medical Sciences, Tehran, Iran,) and with the 1964 Helsinki Declaration and its later amendments or comparable ethical standards.

Informed consent

For this type of study, formal consent is not required.

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Tabatabaei, S.A., Soleimani, M., Vakili, H. et al. The rate of endophthalmitis after pars plana vitrectomy and its risk factors. Int Ophthalmol 39, 1299–1305 (2019). https://doi.org/10.1007/s10792-018-0944-9

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  • DOI: https://doi.org/10.1007/s10792-018-0944-9

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