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A New Prenylated Hydroquinone from the Fruiting Bodies of Ganoderma calidophilum

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Chemistry of Natural Compounds Aims and scope

Prenylated hydroquinones are the main meroterpenoids found in fungal species of the genus Ganoderma. A new prenylated hydroquinone ganocalidin G (1) was isolated from the fruiting bodies of Ganoderma calidophilum. The structure of compound 1 was identified based on 1D and 2D NMR spectroscopy as well as MS. Its absolute structure was elucidated from optical rotation calculation. The bioassay for inhibitory activity against AChE showed compound 1 had weak activity with an inhibition rate of 28.7% at a concentration of 100 μM.

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References

  1. R. A. Mothana, R. Jansen, W. D. Julich, and U. Lindequist, J. Nat. Prod., 63, 416 (2000).

    Article  CAS  PubMed  Google Scholar 

  2. M. C. A. Galappaththi, N. M. Patabendige, B. M. Premarathne, K. K. Hapuarachchi, S. Tibpromma, D. Q. Dai, N. Suwannarach, S. Rapior, and S. C. Karunarathna, Biomolecules, 13, 24 (2023).

    Article  CAS  Google Scholar 

  3. L. Wang, J. Q. Li, J. Zhang, Z. M. Li, H. G. Liu, and Y. Z. Wang, RSC Adv., 10, 42084 (2020).

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  4. D. Cor, Z. Knez, and M. Knez Hrncic, Molecules, 23, 649 (2018).

    PubMed  Google Scholar 

  5. S. Baby, A. J. Johnson, and B. Govindan, Phytochemistry, 114, 66 (2015).

    Article  CAS  PubMed  Google Scholar 

  6. X. R. Peng, S. B. Unsicker, J. Gershenzon, and M. H. Qiu, Nat. Prod. Rep., 40, 1354 (2023).

    Article  CAS  PubMed  Google Scholar 

  7. X. R. Peng, Q. Wang, H. R. Wang, K. Hu, W. Y. **ong, and M. H. Qiu, Bioorg. Chem., 116, 105338 (2021).

    Article  CAS  PubMed  Google Scholar 

  8. Q. Luo, Z. C. Tu, Z. L. Yang, and Y. X. Cheng, Fitoterapia, 125, 273 (2018).

    Article  CAS  PubMed  Google Scholar 

  9. X. R. Peng, R. C. Luo, H. G. Su, L. Zhou, X. Q. Ran, Y. R. Guo, Y. G. Yao, and M. H. Qiu, Org. Chem. Front., 9, 3093 (2022).

    Article  CAS  Google Scholar 

  10. S. Z. Huang, B. H. Cheng, Q. Y. Ma, Q. Wang, F. D. Kong, H. F. Dai, S. Q. Qiu, P. Y. Zheng, Z. Q. Liu, and Y. X. Zhao, RSC Adv., 6, 21139 (2016).

    Article  CAS  Google Scholar 

  11. F. Y. Qin, H. X. Zhang, Q. Q. Di, Y. Wang, Y. M. Yan, W. L. Chen, and Y. X. Cheng, Org. Lett., 22, 2574 (2020).

    Article  CAS  PubMed  Google Scholar 

  12. X. L. Wu, X. L. Mao, G. E. Tuli, B. Song, T. H. Li, Y. X. Zhao, S. L. Chen, N. K. Zeng, S. Z. Huang, T. C. Wen, and C. Y. Deng, Med. Fungi China, 330 (2013).

  13. S. Z. Huang, Q. Y. Ma, F. D. Kong, Z. K. Guo, C. H. Cai, L. L. Hu, L. M. Zhou, Q. Wang, H. F. Dai, W. L. Mei, and Y. X. Zhao, Phytochemistry, 143, 104 (2017).

    Article  CAS  PubMed  Google Scholar 

  14. T. T. Zhang, J. C. Guo, Q. Y. Ma, F. D. Kong, L. M. Zhou, Q. Y. **e, H. F. Dai, Z. F. Yu, and Y. X. Zhao, China J. Chin. Mater. Med., 5, 476 (2021).

    Google Scholar 

  15. G. L. Ellman, K. D. Courtney, V. J. Andres, and R. M. Featherstone, Biochem. Pharmacol., 7, 88 (1961).

    Article  CAS  PubMed  Google Scholar 

  16. Q. Y. Ma, S. Yang, S. Z. Huang, F. D. Kong, Q. Y. **e, H. F. Dai, Z. F. Yu, and Y. X. Zhao, Chem. Nat. Compd., 54, 710 (2018).

    Article  CAS  Google Scholar 

  17. P. Pracht, F. Bohle, and S. Grimme, Phys. Chem. Chem. Phys., 22, 7169 (2020).

    Article  CAS  PubMed  Google Scholar 

  18. M. J. Frisch, G. W. Trucks, H. B. Schlegel, G. E. Scuseria, M. A. Robb, J. R. Cheeseman, G. Scalmani, V. Barone, G. A. Petersson, H. Nakatsuji, X. Li, M. Caricato, A. V. Marenich, J. Bloino, B. G. Janesko, R. Gomperts, B. Mennucci, H. P. Hratchian, J. V. Ortiz, A. F. Izmaylov, J. L. Sonnenberg, D. Williams-Young, F. Ding, F. Lipparini, F. Egidi, J. Goings, B. Peng, A. Petrone, T. Henderson, D. Ranasinghe, V. G. Zakrzewski, J. Gao, N. Rega, G. Zheng, W. Liang, M. Hada, M. Ehara, K. Toyota, R. Fukuda, J. Hasegawa, M. Ishida, T. Nakajima, Y. Honda, O. Kitao, H. Nakai, T. Vreven, K. Throssell, J. A. Montgomery Jr., J. E. Peralta, F. Ogliaro, M. J. Bearpark, J. J. Heyd, E. N. Brothers, K. N. Kudin, V. N. Staroverov, T. A. Keith, R. Kobayashi, J. Normand, K. Raghavachari, A. P. Rendell, J. C. Burant, S. S. Iyengar, J. Tomasi, M. Cossi, J. M. Millam, M. Klene, C. Adamo, R. Cammi, J. W. Ochterski, R. L. Martin, K. Morokuma, O. Farkas, J. B. Foresman, and D. J. Fox, Gaussian 16, Revision C.01, (2019).

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Acknowledgment

This research was supported by the National Natural Science Fund of China (81973568), the Financial Fund of the Ministry of Agriculture and Rural Affairs, P. R. China (NFZX2021), China Agriculture Research System of MOF and MARA (CARS-21).

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Authors and Affiliations

  1. Haikou Key Laboratory for Research and Utilization of Tropical Natural Products & National Key Laboratory for Tropical Crop BreedingInstitute of Tropical Bioscience and BiotechnologyCATAS, 571101, Haikou, P. R. China

    Qing-Yun Ma, Li Yang, Qing-Yi **e, Hao-Fu Dai & You-**ng Zhao

  2. College of Food Science and Technology, Nan**g Agricultural University, 510095, Nan**g, P. R. China

    Ting-Ting Zhang & Zhi-Fang Yu

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  1. Qing-Yun Ma
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  2. Ting-Ting Zhang
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  3. Li Yang
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  4. Qing-Yi **e
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  5. Hao-Fu Dai
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  6. Zhi-Fang Yu
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  7. You-**ng Zhao
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Correspondence to Zhi-Fang Yu or You-**ng Zhao.

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Published in Khimiya Prirodnykh Soedinenii, No. 3, May–June, 2024, pp. 359–362.

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Ma, QY., Zhang, TT., Yang, L. et al. A New Prenylated Hydroquinone from the Fruiting Bodies of Ganoderma calidophilum. Chem Nat Compd 60, 403–406 (2024). https://doi.org/10.1007/s10600-024-04337-z

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  • DOI: https://doi.org/10.1007/s10600-024-04337-z

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