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Risk factors for intraocular pressure elevation during the early period post cataract surgery

  • Clinical Investigation
  • Published:
Japanese Journal of Ophthalmology Aims and scope Submit manuscript

Abstract

Purpose

To assess the risk factors for intraocular pressure (IOP) elevation during the early period post cataract surgery.

Study design

Retrospective study.

Methods

This study involved 1587 eyes that underwent cataract surgery at the Baptist Eye Institute, Kyoto, Japan between April 2020 and May 2021. In all subjects, risk factors for early postoperative IOP elevation (i.e., an increase of IOP of 10 mmHg or more at 1-day postoperative compared with that at baseline, or a postoperative IOP of 28 mmHg or more) were analyzed by multivariate logistic regression analysis.

Results

Of the 1587 treated eyes in this study, 100 (6.3%) experienced early-postoperative IOP elevation. Of those 100 eyes, 78.0% were men, 27.0% had an axial length (AL) of ≥ 26.5 mm, 23.0% had a history of glaucoma treatment, 11.0% had poor mydriasis and 10.0% had intraoperative floppy iris syndrome (IFIS). Multivariate analysis findings revealed that male [odds ratio (OR) 4.36; 95% confidence interval (CI) 2.63–7.23; P < 0.001], AL of ≥ 26.5 mm (3.11; 1.83–5.30; P < 0.001), a history of glaucoma treatment (2.83; 1.63–4.91; P < 0.001), poorly mydriasis (2.63; 1.16–6.01; P = 0.02), IFIS (4.37; 1.78–10.74; P = 0.001) and baseline high IOP (1.09; 1.01–1.18; P = 0.03) were associated with increased IOP during the early period post cataract surgery.

Conclusions

The findings in this study reveal that male sex, high myopia, a history of glaucoma treatment, poor mydriasis, IFIS and baseline high IOP are risk factors for IOP elevation during the early period post cataract surgery.

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Acknowledgements

The authors wish to thank Dr. Hideto Deguchi, Dr. Hideki Fukuoka, Dr. Osamu Hieda, Dr. Tsutomu Inatomi, and Dr. Norihiko Yokoi for their excellent technical support, and Mr. John Bush for editing the manuscript.

Author information

Authors and Affiliations

  1. Department of Ophthalmology, Baptist Eye Institute, Kyoto, Japan

    Hiroaki Oku, Mako Watanabe, Koichi Wakimasu, Kiyoshi Yamamura, Toshihide Yamasaki & Shigeru Kinoshita

  2. Department of Ophthalmology, Kyoto Prefectural University of Medicine, 465 Kajii-cho, Hirokoji-agaru, Kawaramachi-dori, Kamigyo-ku, Kyoto, 602-0841, Japan

    Kazuhiko Mori, Takanori Aoki & Chie Sotozono

  3. Department of Mathematics and Statistics in Medical Science, Kyoto Prefectural University of Medicine, Kyoto, Japan

    Kengo Yoshii

  4. Frontier Medical Science and Technology for Ophthalmology, Kyoto Prefectural University of Medicine, Kyoto, Japan

    Shigeru Kinoshita

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  1. Hiroaki Oku
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Correspondence to Kazuhiko Mori.

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H. Oku, None; K. Mori, None; M. Watanabe, None; T. Aoki, None; K. Wakimasu, None; K. Yamamura, None; T. Yamasaki, None; K. Yoshii, None; C. Sotozono, None; S. Kinoshita, None.

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Corresponding Author: Kazuhiko Mori

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Oku, H., Mori, K., Watanabe, M. et al. Risk factors for intraocular pressure elevation during the early period post cataract surgery. Jpn J Ophthalmol 66, 373–378 (2022). https://doi.org/10.1007/s10384-022-00918-z

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  • DOI: https://doi.org/10.1007/s10384-022-00918-z

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