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Criblage phytochimique et activité antimicrobienne des extraits de Thymus serpyllum et de Thymus vulgaris du mont de Tessala (Algérie occidentale)

Phytochemical screening and antimicrobial activity of extracts of Thymus serpyllum and Thymus vulgaris from the mount of Tessala (Western Algeria)

  • Pharmacognosie
  • Published:
Phytothérapie

Résumé

Les objectifs assignés à la présente étude sont le criblage phytochimique de plusieurs métabolites secondaires et l’évaluation de l’activité antimicrobienne des extraits éthanoliques, décoctés et infusés de Thymus serpyllum L. et de Thymus vulgaris L. Le criblage phytochimique a permis de mettre en évidence la présence de substances ayant de grandes valeurs thérapeutiques (flavonoïdes, tanins…). L’activité antimicrobienne des extraits des taxons choisis vis-à-vis de trois souches bactériennes (Escherichia coli ATTC 25922, Bacillus cereus ATTC 10876 et Proteus mirabilis ATTC 35659) et de deux souches fongiques (Candida albicans ATTC 10231 et Aspergillus brasiliensis ATTC 16404) montre une remarquable activité antibactérienne et antifongique et surtout vis-à-vis de Candida albicans. Les diamètres d’inhibition enregistrés dépassent souvent ceux induits par les antifongiques commercialisés. Par ailleurs, le potentiel antimicrobien des extraits obtenus des feuilles des deux espèces étudiées varie en fonction du type d’extrait testé et de sa concentration, et du type de la souche.

Abstract

The present study aims at evaluating the phytochemical screening of several secondary metabolites and the antimicrobial activities of the ethanolic, decoction, and infused extracts of Thymus serpyllum L. and Thymus vulgaris L. Phytochemistry screening highlighted the presence of substances of high therapeutic value such as flavonoids and tannins. The antimicrobial activity of the extracts of the taxa selected against three bacterial strains (Escherichia coli ATTC 25922, Bacillus cereus ATTC 10876, and Proteus mirabilis ATTC 35659) and two fungal strains (Candida albicans ATTC 10231 and Aspergillus brasiliensis ATTC 16404) showed a remarkable antibacterial and antifungal activity especially against Candida albicans. The inhibition diameters recorded often exceed those induced by commercialized antifungal. On the other hand, the antimicrobial potential of the extracts of the leaves of the two species studied varied depending on the tested extract and its concentration, and on the type of microbial strain.

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Authors and Affiliations

  1. Laboratoire de biodiversité végétale : conservation et valorisation, faculté des sciences de la nature et de la vie, université Djillali-Liabès, BP 89, Haï-Larbi-Ben-M’Hidi, Sidi-Bel-Abbès, 22000, Algérie

    A. Tamert & A. Latreche

  2. Laboratoire de synthèse de l’information environnementale, faculté de médecine, université Djillali-Liabès, Sidi-Bel-Abbès, 22000, Algérie

    L. Aouad

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  1. A. Tamert
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Correspondence to A. Tamert.

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Tamert, A., Latreche, A. & Aouad, L. Criblage phytochimique et activité antimicrobienne des extraits de Thymus serpyllum et de Thymus vulgaris du mont de Tessala (Algérie occidentale). Phytothérapie 15, 384–394 (2017). https://doi.org/10.1007/s10298-017-1132-1

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