Résumé
Eucalyptus globulus (Labill.) [Myrtaceae] est originaire de Tasmanie en Australie et pousse surtout dans les régions chaudes. L’eucalyptus commun ou gommier bleu est un arbre sempervirent qui peut croître jusqu’à 30–55 m de haut. Ses feuilles sont la principale source de son huile essentielle (HE). Utilisée pour ses vertus médicinales, notamment antitussives et expectorantes, elle n’en a pas moins des propriétés fébrifuges, toniques, astringentes, antiseptiques, hémostatiques et vermifuges. Parmi ces composés, le 1,8-cinéole ou eucalyptol (50 à 80 %) est sans doute le plus connu, car c’est un expectorant qui peut soulager la toux et lutter contre les problèmes des voies respiratoires. En outre, pinène, limonène et au moins 250 autres composés dont citronellal, cryptone, pipéritone viendront étoffer la liste des nombreux composés aux vertus médicinales de l’eucalyptus. En phytoaromathérapie, l’essence d’eucalyptus officinal pourra trouver une place comme désinfectant atmosphérique en milieu hospitalier afin de lutter contre les infections nosocomiales et les contaminations aéroportées. Elle aide aussi à lutter contre l’asthme et peut être utilisée pour la désinfection de plaies. Notre travail se veut une revue de la littérature des propriétés thérapeutiques, préventive et/ou curative, de cet arbre à parfum et les potentiels utilisations de son HE en phytoaromathérapie anti-infectieuse ou encore comme ingrédient actif dans les préparations pharmaceutiques.
Abstract
Eucalyptus globulus (Labill.) [Myrtaceae] is native of Tasmania (Australia) and grows mainly in warm regions. The common blue gum eucalyptus is an evergreen tree that can grow up to 30–55 m high. Its leaves are the main source of essential oil (EO), which has been used for medicinal purposes, including antimicrobial and expectorant properties. Further, Eucalyptus globulus EO has many other medicinal properties, such as antipyretic, tonic, astringent, antiseptic, and hemostatic. The chemical composition of EO revealed that the oxygenated monoterpène 1,8-cineol or eucalyptol (50–80%) is the best known probably because it is an expectorant, can relieve cough, and fight against respiratory tract infections. Hence, pinene, limonene, and other compounds (citronellal, cryptone, and piperitone) will expand the list of many compounds with medicinal properties of eucalyptus EO. In phytotherapy research, Eucalyptus globulus EO could be used as an air disinfectant in hospitals to fight against nosocomial infections and airborne contaminations. Our article aims to be a literature review of the therapeutic (preventive or curative) properties of Eucalyptus globulus and gives a strong impetus of the potential uses of EO in aromatherapy or as an active ingredient in pharmaceutical industry.
Références
Batish DR, Singh HP, Kohli RK et al (2008) Eucalyptus essential oil as a natural pesticide. Forest Ecol Manag 256:2166–74
Martinetti P (2013) Mon guide des huiles essentielles. Éditions Fernand Lanore, Paris, France
Botineau M (2010) Botanique systématique et appliquée des plantes à fleurs. Éditions Tec & Doc, Lavoisier, Paris, France
Louppe D (2008) PROTA: Ressources végétales de l’Afrique tropicale. Backhuys Publishers, Wageningen, Pays-Bas (site web: http://www.prota4u.org/)
Lis-Balchin M (2006) Aromatherapy science: a guide for healthcare professionals. Pharmaceutical Press, Londres, Grande-Bretagne
Leicach SR, Guarnaschelli AB, Garau AM et al (2012) Chemical defenses in Eucalyptus species: a sustainable strategy based on antique knowledge to diminish agrochemical dependency. Intech Open Access Publisher, NY, USA
Goetz P, Ghedira K (2012) Phytothérapie anti-infectieuse. Springer-Verlag, Paris, France
Brooker MIH, Kleinig DA (2004) Field guide to eucalypts, Northern Australia. Bloomings Books, Melbourne, Australie
Boullard B (2001) Plantes médicinales du monde: croyances et réalités. Éditions De Boeck Secundair, Paris, France
Ait Youssef M (2006) Plantes médicinales de Kabylie. Éditions Ibispress, Paris, France
Coppen JJW (2002) Eucalyptus: the genus Eucalyptus. Medicinal and aromatic plants — industrial profiles. Volume 22. Edition Taylor & Francis, Londres, Grande-Bretagne
Silvant C (2015) L’aromathérapie: la nature au service de l’humanité. Éditions Publibook, Paris, France
Mulyaningsih S, Sporer F, Zimmermann S, et al (2010) Synergistic properties of the terpenoids aromadendrene and 1,8-cineole from the essential oil of Eucalyptus globulus against antibiotic-susceptible and antibiotic-resistant pathogens. Phytomedicine 17:1061–6
Goldbeck JC, Do Nascimento JE, Jacob RG, et al (2014) Bioactivity of essential oils from Eucalyptus globulus and Eucalyptus urograndis against planktonic cells and biofilms of Streptococcus mutans. Ind Crops Prod 60:304–9
Vilela GR, de Almeida GS, Brito JO, et al (2009) Activity of essential oil and its major compound, 1,8-cineole, from Eucalyptus globulus Labill., against the storage fungi Aspergillus flavus Link and Aspergillus parasiticus Speare. J Stor Prod Res 45:108–11
Elaissi A, Rouis Z, Salem NAB, et al (2012) Chemical composition of 8 Eucalyptus species’ essential oils and the evaluation of their antibacterial, antifungal and antiviral activities. BMC Complement Altern Med 12:81
Manika N, Chanotiya CS, Negi MPS, et al (2013) Copious shoots as a potential source for the production of essential oil in Eucalyptus globulus. Ind Crops Prod 46:80–4
Kumar P, Mishra S, Malik A, et al (2012) Compositional analysis and insecticidal activity of Eucalyptus globulus (family: Myrtaceae) essential oil against housefly (Musca domestica). Act Trop 122:212–8
Tyagi AK, Malik A (2011) Antimicrobial potential and chemical composition of Eucalyptus globulus oil in liquid and vapour phase against food spoilage microorganisms. Food Chem 126:228–35
Boukhatem MN, Ferhat MA, Kameli A, et al (2014) Liquid and vapour phase antibacterial activity of Eucalyptus globulus essential oil = susceptibility of selected respiratory tract pathogens. Am J Infect Dis 10:105
Chalchat JC, Muhayimana A, Habimana JB, et al (1997) Aromatic plants of Rwanda: chemical composition of essential oils of ten Eucalyptus species growing in Ruhande arboretum, Butare, Rwanda. J Essent Oil Res 9:159–65
Bruneton J (1999) Huiles essentielles. Pharmacognosie, phytochimie, plantes médicinales. Éditions Tec & Doc, 3e édition, Lavoisier, Paris, France
Dorman HJD, Deans SG (2000) Antimicrobial agents from plants: antibacterial activity of plant volatile oils. J Appl Microbiol 88:308–16
Cimanga K, Kambu K, Tona L, et al (2002) Correlation between chemical composition and antibacterial activity of essential oils of some aromatic medicinal plants growing in the Democratic Republic of Congo. J Ethnopharmacol 79:213–20
Sartorelli P, Marquioreto AD, Moreno PRH (2007) Chemical composition and antimicrobial activity of the essential oils from two species of Eucalyptus. Phytother Res 21:231–3
Bouaoun D, Hilan C, Garabeth F, et al (2007) Étude de l’activité antimicrobienne de l’huile essentielle d’une plante sauvage Prangos asperula Boiss. Phytothérapie 5:129–34
Pitarokili D, Tzakou O, Loukis A, Harvala C (2003) Volatile metabolites from Salvia fruticosa as antifungal agents in soil borne pathogens. J Agr Food Chem 51:3294–301
Sonboli A, Babakhani B, Mehrabian AR (2006) Antimicrobial activity of six constituents of essential oil from Salvia. Zeitschrift Naturforschung C 61:160–4
Sallé JL (1991) Le totum en phytothérapie, approche de la phytobiothérapie. Éditions Frison-Roche, Paris, France
Pattnaik S, Subramanyam VR, Bapaji M, Kole CR (1997) Antibacterial and antifungal activity of aromatic constituents of essential oils. Microbios 89:39–46
Đakov T (2011) Antimicrobial effect of essential oil isolated from Eucalyptus globulus Labill. from Montenegro. Czech J Food Sci 29:277–84
Proenza YG, Álvarez RQ, Tamayo V, Garcia YS (2013) Chemical composition and antibacterial activity of the essential oil from Eucalyptus pellita. J Med Plants Res 7:1979–83
Deans SG, Ritchie G (1987) Antibacterial properties of plant essential oils. Inter J Food Microbiol 5:165–80
Prabuseenivasan S, Jayakumar M, Ignacimuthu S (2006) In vitro antibacterial activity of some plant essential oils. BMC Complement Altern Med 6:39
Burt S (2004) Essential oils: their antibacterial properties and potential applications in foods-a review. Inter J Food Microbiol 94:223–53
Gilly G (1997) Les plantes à parfum et huiles essentielles à Grasse: botanique, culture, chimie, production et marché. Éditions L’Harmattan, Paris, France
Hyldgaard M, Mygind T, Meyer RL (2012) Essential oils in food preservation: mode of action, synergies, and interactions with food matrix components. Front Microbiol 3:1-12
Laird K, Phillips C (2012) Vapour phase: a potential future use for essential oils as antimicrobials? Lett Appl Microbiol 54:169–174
Inouye S, Takizawa T, Yamaguchi H (2001) Antibacterial activity of essential oils and their major constituents against respiratory tract pathogens by gaseous contact. J Antimicrob Chemoth 47:565–73
Bachir Raho G, Benali M (2008) Antibacterial activity of leaf essential oils of Eucalyptus globulus and Eucalyptus camaldulensis. Afr J Pharm Pharmacol 2:211–5
Bachir Raho G, Benali M (2012) Antibacterial activity of the essential oils from the leaves of Eucalyptus globulus against Escherichia coli and Staphylococcus aureus. Asian Pac J Trop Biomed 2:739–42
Abe S, Sato Y, Inoue S, et al (2002) Anti-Candida albicans activity of essential oils including Lemongrass (Cymbopogon citratus) oil and its component, citral. Japan J Med Mycol 44:285–91
Goni P, López P, Sánchez C, et al (2009) Antimicrobial activity in the vapour phase of a combination of cinnamon and clove essential oils. Food Chem 116:982–9
Carson CF, Hammer KA (2011) Chemistry and bioactivity of essential oils. Lipids and essential oils as antimicrobial agents. John Wiley & Sons, Chichester, Royaume-Uni
ESCOP, European Scientific Cooperative on Phytotherapy (2003) ESCOP Monographs: The Scientific Foundation for Herbal Medicinal Products. Edition Thieme Verlag, Stuttgart, Allemagne
Festy D, Pacchioni I (2014) Guide de poche d’aromathérapie: 41 huiles essentielles pour se soigner en toute simplicité. Éditions Quotidien Malin, France
Silva J, Abebe W, Sousa SM, et al (2003) Analgesic and antiinflammatory effects of essential oils of Eucalyptus. J Ethnopharmacol 89:277–83
Vigo E, Cepeda A, Perez-Fernandez R, Gualillo O (2004) In vitro anti-inflammatory effect of Eucalyptus globulus and Thymus vulgaris: nitric oxide inhibition in J774A.1 murine macrophages. J Pharm Pharmacol 56:257–63
Tsai ML, Lin CC, Lin WC, Yang CH (2011) Antimicrobial, antioxidant, and anti-inflammatory activities of essential oils from five selected herbs. Biosci Biotechnol Biochem 75:1977–83
Medeiros KC, Monteiro JC, Medeiros I, et al (2007) Effect of the activity of the Brazilian polyherbal formulation: Eucalyptus globulus Labill., Peltodon radicans Pohl. and Schinus terebinthifolius Radd. in inflammatory models. Rev Brasil Farmacogn 17:23–8
Kaloustian J, Hadji-Minaglou F (2012) La connaissance des huiles essentielles: qualitologie et aromathérapie: entre science et tradition pour une application médicale raisonnée. Coll. « Phytothérapie pratique ». Springer-Verlag, Paris, France
Day LM, Ozanne-Smith J, Parsons BJ, et al (1997) Eucalyptus oil poisoning among young children: mechanisms of access and the potential for prevention. Austral N Zealand J Publ Health 21:297–302
Matthys H, de Mey C, Carls C, et al (2000) Efficacy and tolerability of myrtol standardized in acute bronchitis. A multi-centre, randomised, double-blind, placebo-controlled parallel group clinical trial vs. cefuroxime and ambroxol. Arzneimittel-Forschung 50:700–11
Behrbohm H, Kaschke O, Sydow K (1995) Effect of the phytogenic secretolytic drug Gelomyrtol forte on mucociliary clearance of the maxillary sinus. Laryngorhinootologie 74:733–7
Meister R, Wittig T, de Mey C (1999) Efficacy and tolerability of myrtol standardized in long-term treatment of chronic bronchitis. Arzneim-Forsch 49:351–8
Federspil P, Wulkow R, Zimmermann T (1997) Effects of standardized myrtol in therapy of acute sinusitis: results of a doubleblind, randomized multicenter study compared with placebo. Laryngorhinootologie 76:23–7
Worth H, Schacher C, Dethlefsen U (2009) Concomitant therapy with cineole (eucalyptol) reduces exacerbations in COPD: a placebo-controlled double-blind trial. Respir Res 10:69
Juergens UR, Dethlefsen U, Steinkamp G, et al (2003) Antiinflammatory activity of 1.8-cineol (eucalyptol) in bronchial asthma: a double-blind placebo-controlled trial. Respir Med 97:250–6
Kehrl W, Sonnemann U, Dethlefsen U (2004) Therapy for acute nonpurulent rhinosinusitis with cineole: results of a double-blind, randomized, placebo-controlled trial. Laryngoscope 114:738–42
Tesche S, Metternich F, Sonnemann U, et al (2008) The value of herbal medicines in the treatment of acute non-purulent rhinosinusitis. Eur Arch Otorhinolaryngol 265:1355–9
Cermelli C, Fabio A, Fabio G, Quaglio P (2008) Effect of Eucalyptus essential oil on respiratory bacteria and viruses. Curr Microbiol 56:89–92
Santos FA, Rao VSN (2000) Anti-inflammatory and antinociceptive effects of 1,8-cineole a terpenoid oxide present in many plant essential oils. Phytother Res 14:240–4
Grassmann J, Hippeli S, Dornisch K, Elstner EF (2000) Antioxidant properties of essential oils. Possible explanations for their anti-inflammatory effects. Arzneimittel-Forschung 50:135–9
Kim MJ, Nam ES, Paik SI (2005) The effects of aromatherapy on pain, depression, and life satisfaction of arthritis patients. Taehan Kanho Hakhoe Chi 35:186–94
Osawa K, Yasuda H, Morita H, et al (1996) Macrocarpals H, I, and J from the leaves of Eucalyptus globulus. J Nat Prod 59:823–7
Fine DH, Furgang D, Barnett ML, et al (2000) Effect of an essential oil containing antiseptic mouth rinse on plaque and salivary Streptococcus mutans levels. J Clin Periodontol 27:157–61
Charles CH, Sharma NC, Galustians HJ, et al (2001) Comparative efficacy of an antiseptic mouth rinse and an antiplaque/antigingivitis dentifrice: a six-month clinical trial. J Am Dent Assoc 132:670–5
Baudoux D (2001) L’aromathérapie — Se soigner par les huiles essentielles. Éditions Atlantica, Paris, France
Gardulf A, Wohlfart I, Gustafson R (2004) A prospective crossover field trial shows protection of lemon Eucalyptus extract against tick bites. J Med Entomol 41:1064–7
Kirton LG (2005) Laboratory and field tests of the effectiveness of the lemon-eucalyptus extract, citridiol, as a repellent against land leeches of the genus Haemadipsa (Haemadipsidae). Ann Trop Med Parasitol 99:695–714
Dehghani-Samani A, Madreseh-Ghahfarokhi S, Dehghani-Samani A, et al (2015) Acaricidal and repellent activities of essential oil of Eucalyptus globulus against Dermanyssus gallinae (Acari: Mesostigmata). J Herbmed Pharmacol 4:81–4
Rossi YE, Palacios SM (2015) Insecticidal toxicity of Eucalyptus cinerea essential oil and 1,8-cineole against Musca domestica and possible uses according to the metabolic response of flies. Ind Crops Prod 63:133–7
Chauhan N, Malik A, Sharma S, Dhiman RC (2016) Larvicidal potential of essential oils against Musca domestica and Anopheles stephensi. Parasitol Res 115:2223–31
White DA, Beadle CL, Worledge D, Honeysett JL (2016) Wood production per evapotranspiration was increased by irrigation in plantations of Eucalyptus globulus and Eucalyptus nitens. New Forests 47:303–17
Harkat-Madouri L, Asma B, Madani K, et al (2015) Chemical composition, antibacterial and antioxidant activities of essential oil of Eucalyptus globulus from Algeria. Ind Crops Prod 78:148–53
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Boukhatem, M.N., Ferhat, M.A., Kameli, A. et al. Eucalyptus globulus (Labill.) : un arbre à essence aux mille vertus. Phytothérapie (2017). https://doi.org/10.1007/s10298-017-1114-3
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DOI: https://doi.org/10.1007/s10298-017-1114-3