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Corrélation entre la composition chimique et l’activité antifongique des huiles essentielles à prédominance thymol sur Candida albicans et Aspergillus fumigatus

Correlation between chemical composition and antifungal activity of essential oils predominated by thymol on Candida albicans and Aspergillus fumigatus

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  • Aromathérapie-Recherche
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Phytothérapie

Résumé

L’analyse des huiles essentielles (HE) des graines d’Aframomum melegueta (K. Schum), des feuilles d’Ocimum gratissimum, d’Aframomum daniellii (K. Hook) et d’Aframomum exscapum (H. Sims), obtenues par hydrodistillation à l’aide d’un appareil de type Clevenger, a été réalisée par la CPG et la CPG/SM. L’étude de l’activité antifongique de ces échantillons sur la croissance de Candida albicans et Aspergillus fumigatus a permis de les classer en trois groupes en fonction de leurs réponses antifongiques et de leurs chémotypes.

Abstract

The analysis of essential oils of seeds of Aframomum melegueta (K. Schum), the leaves of Ocimum gratissimum, Aframomum daniellii (K. Hook) and Aframomum exscapum (H. Sims) obtained by steam distillation using Clevenger apparatus, was performed by GC and GC / MS. The study of antifungal activity of these samples on the growth of Candida albicans and Aspergillus fumigatus allowed classifying them into three groups according to their antifungal response in correlation with their chemotypes.

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Authors and Affiliations

  1. Laboratoire de chimie biologique, UFR SSMT, université de Cocody-Abidjan, Abidjan, Côte-d’Ivoire, Afrique

    A. M. Koffi & Z. F. Tonzibo

  2. Laboratoire SVFp, EA 4233 « Nutrition, cancérogenèse et thérapie antitumorale », UFR pharmacie, université d’Auvergne, Clermont-Ferrand, France

    L. Delort, N. Ruiz & L. Caldefie-Chézet

  3. Laboratoire de chimie des glucides, des hétérocycles et des huiles essentielles, université Blaise-Pascal, Clermont-Ferrand, France

    J. C. Chalchat

Authors
  1. A. M. Koffi
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  2. Z. F. Tonzibo
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  3. L. Delort
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  4. N. Ruiz
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  5. L. Caldefie-Chézet
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  6. J. C. Chalchat
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Correspondence to Z. F. Tonzibo.

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Koffi, A.M., Tonzibo, Z.F., Delort, L. et al. Corrélation entre la composition chimique et l’activité antifongique des huiles essentielles à prédominance thymol sur Candida albicans et Aspergillus fumigatus . Phytothérapie 11, 134–139 (2013). https://doi.org/10.1007/s10298-013-0767-9

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  • DOI: https://doi.org/10.1007/s10298-013-0767-9

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