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Is scintigraphy necessary to detect migration of 125I seeds after brachytherapy for early prostate cancer?

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Abstract

Background

We investigated whether scintigraphy was superior to radiography for detecting migrated seeds after brachytherapy for prostate cancer.

Methods

We studied 57 patients with early prostate cancer who were treated with free 125I transperineal brachytherapy. Scintigraphy was used to detect seed migration on postoperative day (POD) 1, radiography was used on POD 2, and both tests were used on POD 30.

Results

The total number of implanted seeds in this study was 3,753 in 57 patients. Overall, there were 19 seed migrations in 12 patients. On POD 1, there were 4 seed migrations in 4 patients that were detected by scintigraphy. On POD 2, there were 10 seed migrations in 9 patients that were detected by radiography. On POD 30, 17 seed migrations were detected in 10 patients by radiography and 18 seeds migrations were detected by scintigraphy. However, 1 seed migration which was located outside of the detectable range of radiography was detected only by scintigraphy.

Conclusions

Both scintigraphy and radiography have similar abilities to detect migrated seeds 1 month after 125I brachytherapy for prostate cancer. While both tests have advantages and disadvantages, it is reasonable to only use radiography if scintigraphy is not available.

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Authors and Affiliations

  1. Department of Urology, Tokyo Medical University, 6-7-1 Nishi-shinjuku, Shinjuku-ku, Tokyo-to, 160-0023, Japan

    Yu Odagaki, Makoto Ohori, Jun Nakshima, Yoshio Ohno & Masaaki Tachibana

  2. Department of Radiology, Tokyo Medical University, Tokyo-to, 160-0023, Japan

    Mana Yoshimura, Ryuji Mikami, Hidetsugu Nakayama & Koichi Tokuuye

Authors
  1. Yu Odagaki
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  2. Makoto Ohori
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  3. Mana Yoshimura
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  4. Jun Nakshima
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  5. Yoshio Ohno
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  6. Ryuji Mikami
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  7. Hidetsugu Nakayama
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  8. Koichi Tokuuye
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  9. Masaaki Tachibana
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Corresponding author

Correspondence to Makoto Ohori.

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The authors declare that they have no conflict of interest.

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Odagaki, Y., Ohori, M., Yoshimura, M. et al. Is scintigraphy necessary to detect migration of 125I seeds after brachytherapy for early prostate cancer?. Int J Clin Oncol 21, 397–401 (2016). https://doi.org/10.1007/s10147-015-0901-9

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  • DOI: https://doi.org/10.1007/s10147-015-0901-9

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