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RETRACTED ARTICLE: Comparison of preoperative ultrasound and MRI in the diagnosis of microvascular invasion in hepatocellular carcinoma

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This article was retracted on 11 May 2024

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Abstract

Ultrasound has few reports on its application in prediction of microvascular invasion (MVI) in hepatocellular carcinoma (HCC). The purpose of this study was to explore the diagnostic efficacies of preoperative ultrasound and magnetic resonance imaging (MRI) for HCC MVI and compare these two imaging methods for the diagnosis of this condition. The clinical and preoperative ultrasound and MR imaging data of 26 patients with newly diagnosed HCC were collected between October 2020 and October 2021. According to the gold standard (postoperative pathology), the patients were divided into MVI-positive and MVI-negative groups, and the efficacies of ultrasound and MRI in diagnosing HCC MVI and the consistency between the two imaging modalities were analyzed. For the preoperative diagnosis of MVI using ultrasound, the sensitivity was 93.33%, the specificity was 81.82%, and the accuracy was 88.46%. For preoperative MRI, the sensitivity was 66.67%, the specificity was 100%, and the accuracy was 80.77%. In diagnosing MVI, the two methods had significantly different efficacy (P = 0.031). Ultrasound and MRI have high diagnostic efficiency for MVI, but the accuracy of preoperative MRI was lower than that of preoperative ultrasound. These results indicate that ultrasound has a certain guiding significance in the diagnosis of HCC MVI.

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Data availability

The datasets used during the current study are available from the corresponding author on reasonable request.

Change history

Abbreviations

BC:

Breast cancer

HR :

Hazard ratio

CI :

Confidence interval

KM‑plot :

Kaplan‑Meier plotter

OS :

Overall survival

RFS :

Relapse‑free survival

DMFS :

Distant metastasis‑free survival

PPS :

Post‑progression survival

ER :

Estrogen receptor

PR :

Progesterone receptor

HER2 :

Human epidermal growth factor receptor

TP53 :

Tumor protein p53

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Funding

Liuzhou Science and Technology Department research program (Grant No.2022CAC0108).

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Author notes

  1. Yunmin Long and Zheng Lv contributed equally to this work.

Authors and Affiliations

  1. Department of Ultrasound, Guilin Medical University Affiliated Hospital, Guilin, 541001, China

    Yunmin Long, Bing Tang & Qin Li

  2. Department of Radiology, Guilin Medical University Affiliated Hospital, Guilin, 541001, China

    Zheng Lv & Shaoyi Wang

  3. Department of Radiology, Liuzhou People’s Hospital Affiliated to Guangxi Medical University, Chengzhong District, 8 Wenchang Road, Liuzhou, 545006, China

    Wei Zhang

Authors
  1. Yunmin Long
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  2. Zheng Lv
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  4. Bing Tang
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  6. Wei Zhang
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Contributions

WZ designed the study. YL, ZL, SW, BT, and QL performed data analysis. YL and ZL drafted the manuscript. WZ revised the manuscript. All authors read and approved the final manuscript.

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Correspondence to Wei Zhang.

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This study was approved by the Institutional Ethics Committee of Guilin Medical University Affiliated Hospital.

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Obtained.

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The authors declare no competing interests.

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This article has been retracted. Please see the retraction notice for more detail: https://doi.org/10.1007/s10142-024-01376-1

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Long, Y., Lv, Z., Wang, S. et al. RETRACTED ARTICLE: Comparison of preoperative ultrasound and MRI in the diagnosis of microvascular invasion in hepatocellular carcinoma. Funct Integr Genomics 23, 100 (2023). https://doi.org/10.1007/s10142-023-01006-2

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  • DOI: https://doi.org/10.1007/s10142-023-01006-2

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