Zusammenfassung
Vorrangige Indikation zur retroperitonealen Lymphadenektomie (RLA) beim Hodentumor ist die Residualtumorresektion. Als primäre Maßnahme in den klinischen Stadien I und IIA/B beim Nichtseminom ist die Operation heute kaum noch von Bedeutung. Gerade für letztgenannte Indikationen wäre alternativ zum offenen Vorgehen die Laparoskopie geeignet, während sie bei der Residualtumorresektion nur für kleine Restbefunde in Frage kommt. Die onkologischen Langzeitergebnisse sind mit denen der offenen Operation vergleichbar, auch ist ein nervschonendes Vorgehen möglich, vorausgesetzt, es handelt sich um einen laparoskopisch versierten Operateur.
Abstract
The strongest indication to perform retroperitoneal lymph node dissection (RPLND) in testicular cancer is for removal of residual disease after chemotherapy in advanced nonseminoma. As a primary option for stage I or small volume metastatic nonseminoma RPLND has lost its importance today. Nevertheless, especially these are the stages where surgery can be performed laparoscopically, while in cases of residual tumor resection only small residuals can be removed with this technique. The oncological long-term results of laparoscopic RPLND are comparable to open surgery; nerve sparing is possible, provided that the surgeon has sufficient experience with laparoscopy. RPLND is not an operation to learn laparoscopy.
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Literatur
Albers P, Siener R, Kliesch S et al. (2003) Risk factors for relapse in clinical stage I nonseminomatous testicular germ cell tumors: results of the German Testicular Cancer Study Group trial. J Clin Oncol 21: 1505–1512
Heidenreich A, Sesterhenn IA, Mostofi FK et al. (1998) Prognostic factors that identify patients with clinical stage I nonseminomatous germ cell tumors at low risk and high risk for metastasis. Cancer 83: 1002–1011
Ondrus D, Matoska J, Belan V et al. (1998) Prognostic factors in clinical stage I nonseminomatous germ cell testicular tumors: rationale for different risk-adapted treatment. Eur Urol 33: 562–566
Read G, Stenning SP, Cullen MH et al. (1992) Medical Research Council prospective study of surveillance for stage I testicular teratoma. Medical Research Council Testicular Tumors Working Party. J Clin Oncol 10: 1762–1768
Klepp O, Dahl O, Flodgren P et al. (1997) Risk-adapted treatment of clinical stage I non-seminoma testis cancer. Eur J Cancer 33: 1038–1044
Schmoll H-J, Souchon R, Krege S et al. (2004) European consensus on diagnosis and treatment of germ cell cancer: a report of the European Germ Cell Cancer Consensus Group (EGCCCG). Ann Oncol 15: 1377–1399
Weißbach L, Boedefeld EA, Horstmann-Dubral B et al. (1990) Surgical treatment of stage I non-seminomatous germ cell testis tumor. Eur Urol 17: 97–106
Donohue JP, Thornhill JA, Foster RS et al. (1993) Retroperitoneal lymphadenectomy for clinical stage A testis cancer (1965–1989): modifications of technique and impact on ejaculation. J Urol 149: 237–243
Rassweiler JJ, Frede T, Lenz E et al. (2000) Long-term experience with laparoscopic retroperitoneal lymph node dissection in the management of low – stage testis cancer. Eur Urol 37: 251–260
Hsu TH, Su LM, Ong A (2003) Anterior extraperitoneal approach to laparoscopic retroperitoneal lymph node dissection: a novel technique. J Urol 169: 258–260
Steiner H, Peschel R, Janetschek G et al. (2004) Long-term results of laparoscopic retroperitoneal lymph node dissection: a single-center 10-year experience. Urology 62: 550–555
Hara I, Kawabata G, Yamada Y et al. (2004) Extraperitoneal laparoscopic retroperitoneal lymph node dissection in supine position after chemotherapy for advanced testicular carcinoma. Int J Urol 11: 934–939
Nelson JB, Chen RN, Bishoff JT et al. (1999) Laparoscopic retroperitoneal lymph node dissection for clinical stage I nonseminomatous germ cell testicular tumors. Urology 54: 1064–1967
Corvin S, Sturm W, Kuczyk M et al. (2005) Laparoscopic retroperitoneal lymphadenectomy in the management of low – stage testicular cancer: technique and results. Minim Invasive Ther Allied Technol 14: 52–56
Corvin S, Sturm W, Schlatter E et al. (2005) Laparoscopic retroperitoneal lymph-node dissection with the waterjet is technically feasible and safe in testis-cancer patient. J Endourol 19: 823–882
Corvin S, Kuczyk M, Anastasiadis A, Stenzl A (2004) Laparoscopic retroperitoneal lymph node dissection for nonseminomatous testicular carcinoma. World J Urol 22: 33–36
Peschel R, Gettman MT, Neururer R et al. (2002) Laparoscopic retroperitoneal lymph node dissection: descriptionof the nerve – sparing technique. Urology 60: 339–343
Janetschek G, Hobisch A, Peschel R et al. (2000) Laparoscopic retroperitoneal lymph node dissection for clinical stage I nonseminomatous testicular carcinoma: Long-term outcome J Urol 163: 1793–1796
Höltl L, Peschel R, Knapp R et al. (2002) Primary lymphatic metastatic spread in testicular cancer occurs ventral to the lumbar vessels. Urology 59: 114–118
Janetschek G, Hobisch A, Hittmair A et al. (1999) Laparoscopic retroperitoneal lymphadenectomy after chemotherapy for stage IIB nonseminomatous testicular carcinoma. J Urol 151: 477–481
Rassweiler JJ, Seemann O, Henkel TO et al. (1996) Laparoscopic retroperitoneal lymph node dissection for nonseminomatous germ cell tumors: Indications and limitations. J Urol 156: 1108–1113
Albers P, Weißbach L, Krege S et al. (2004) Prediction of necrosis after chemotherapy of advanced germ cell tumors – results of a prospective multicenter trial of the GTCSG. J Urol 171: 1835–1838
Wit M de, Hartmann M, Brenner W et al. (2006) (18F)-FDG-PET in germ cell tumors following chemotherapy: Results of the German multicenter trial. JCO 24: 222; Abstr. 4521
De Santis M, Bokemeyer C, Becherer A et al. (2001) Predictive impact of 2–18 fluoro-2-deoxy-D-glucose positron emission tomography for residual postchemotherapy masses in patients with bulky seminoma. J Clin Oncol 19: 3740–3744
Rabbani F, Goldenberg SL, Gleave ME et al. (1998) Retroperitoneal lymphadenectomy for post-chemotherapy residual masses: is a modified dissection and resection of the residual mass sufficient? Br J Urol 81: 295–300
Sheinfeld J (2002) The role of adjunctive postchemotherapy surgery for nonseminomatous germ-cell tumors: current concepts and controversies. Semin Urol Oncol 20: 262–271
Palese MA, Su LM, Kavoussi LR (2002) Laparoscopic retroperitoneal lymph node dissection after chemotherapy. Urology 60: 130–134
Schmoll HJ, Beyer J (1998) Prognostic factors in metastatic germ cell tumors. Semin Oncol 25: 174–185
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Kuczyk, M., Krege, S. Retroperitoneale Lymphadenektomie bei Hodentumoren. Onkologe 14, 587–592 (2008). https://doi.org/10.1007/s00761-008-1360-y
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DOI: https://doi.org/10.1007/s00761-008-1360-y