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Comparison of bicarbonate and base excess values analyzed by four different blood gas analyzers

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Abstract

Comparison of the calculation formula, reproducibility, correlation and variation of bicarbonate ion concentration (HCO3 ), and base excess value (BE) among four blood-gas analyzers was performed. No HCO3 and BE values calculated from the formulas showed any clinically significant difference, and all analyzers showed good correlation on their measurements. On the actual measurement of a specific sample, however, BE values from the same sample ranged between −6.3 and −15.7, which might affect therapeutic strategy. Caution should be taken for the assessment of data if different types of blood-gas analysis devices are used in the same facility.

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References

  1. K Suwa (1991) Blood gases in medicine, 2nd edn Chugai-Igaku Tokyo 1–4

    Google Scholar 

  2. IH Gøthgen O Siggaard-Andersen G Kokholm (1990) ArticleTitleVariations in the hemoglobin-oxygen dissociation curve in 10 079 arterial blood samples Scand Clin Lab Invest 50 IssueIDSuppl 203 87–90

    Google Scholar 

  3. CFR 405: Clinical Laboratory Improvement Amendments of 1988, Final Rule, Subpart P. Federal Register February 1992; no 493. 1701-.1721, pp 7183–7184

  4. RG Bates (1954) Electrometric pH determinations John Wiley and Sons New York

    Google Scholar 

  5. T Maekawa Y Okuda DG McDowall (1980) ArticleTitleEffect of low concentrations of halothane on the oxygen electrode Br J Anaesth 52 585–587 Occurrence Handle7426229 Occurrence Handle10.1093/bja/52.6.585 Occurrence Handle1:CAS:528:DyaL3cXks1Gju7o%3D

    Article  PubMed  CAS  Google Scholar 

  6. MC Sanz (1957) ArticleTitleUltramicro methods and standardization of equipment Clin Chem 3 406–419 Occurrence Handle13461351 Occurrence Handle1:CAS:528:DyaG1cXns1Kq

    PubMed  CAS  Google Scholar 

  7. O Siggaard-Andersen PD Wimberley N Fogh-Andersen IH Gøthgen (1988) ArticleTitleMeasured and derived quantities with modern pH and blood gas equipment: calculation algorithms with 54 equations Scand J Clin Lab Invest 48 IssueIDSuppl 189 77–85 Occurrence Handle1:CAS:528:DyaL1MXhtFSqurY%3D Occurrence Handle10.3109/00365518809168194

    Article  CAS  Google Scholar 

  8. O Siggaard-Andersen (1974) The acid-base status of the blood, 4th edn Munksggard Copenhagen

    Google Scholar 

  9. Christiansen TF (1981) An algorithm for calculating the concentration of the base excess of blood. In: Siggaard-Andersen O (ed) Proc IFCC Workshop. Radiometer A/s: Copenhagen

  10. National Committee for Clinical Laboratory Standards (1991) Definitions of quantities and conventions related to blood, pH and gas analysis, second edn. NCCLS, Wayne, PA, USA (currently: CLSI), 11:1–11

  11. National Committee for Clinical Laboratory Standards (1982) Tentative standard for definitions of quantities and conventions related to blood pH and gas analysis. NCCLS, Wayne, PA, USA (currently: CLSI), 2:10

  12. National Committee for Clinical Laboratory Standards (1994) Definitions of quantities and conventions related to blood pH and gas analysis; approved standard; NCCLS Document C12-A (Vol. 14, No. 11); NCCLS, Wayne, PA, USA (currently: CLSI)

  13. Shapiro BA, Peruzzi WT, Kozelowski-Templin R (1993) Metabolic acid-base balance. In: Shapiro BA, Peruzzi WT, Kozelowski-Templin R (eds) Clinical application of blood gases, 5th edn. Mosby St Louis, pp 5–6

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Nakamaru, K., Hatakeyama, N., Yamada, M. et al. Comparison of bicarbonate and base excess values analyzed by four different blood gas analyzers. J Anesth 21, 429–432 (2007). https://doi.org/10.1007/s00540-007-0509-y

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  • DOI: https://doi.org/10.1007/s00540-007-0509-y

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