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Timing of voiding cystourethrography in infants with first time urinary infection

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Abstract

The aim of the study was to evaluate whether the timing of performing a voiding cystourethrography (VCUG) following a first urinary tract infection (UTI) in infants is related to the presence or the severity of vesicoureteral reflux (VUR). A total of 411 children (male 230, female 181) with a first-recognised UTI between ages 15 days and 12 months (median 3 months) underwent a VCUG within 4–81 days (median 9 days) following diagnosis. The presence and the grade of the VUR were compared in two groups: an “early” group in which the VCUG was performed during the first week of the start of treatment and a “late” group in which the examination was performed during the second week or thereafter. The prevalence of VUR in the study cohort was 23.3% (96/411 infants). A VUR was diagnosed in 44 infants in the early group (28%) and in 52 in the late group (21%). Reflux of grade III or higher was seen in 25/44 (57%) of the infants in the early group and in 27/52 (52%) infants in the late group. These differences were not significant. Our results suggest that neither the presence nor the grade of VUR in infants is influenced by the timing of the examination following diagnosis. We therefore recommend that it is better to perform VCUG as soon as possible, provided the inflammation has subsided.

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Authors and Affiliations

  1. 1st Department of Pediatrics, P. and A. Kyriakou Children’s Hospital, Athens, Greece

    Dimitrios Doganis, Mersini Mavrikou, Dimitrios Delis & Lela Stamoyannou

  2. 3rd Department of Pediatrics, P. and A. Kyriakou Children’s Hospital, Athens, Greece

    Konstantinos Siafas

  3. 2nd Department of Pediatrics, Athens University Medical School, P. and A. Kyriakou Children’s Hospital, Athens, Greece

    Konstantinos Sinaniotis

  4. 12, Kapetan Petroutsou Str, 11523, Athens, Greece

    Dimitrios Doganis

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  1. Dimitrios Doganis
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  2. Mersini Mavrikou
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  3. Dimitrios Delis
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  4. Lela Stamoyannou
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  5. Konstantinos Siafas
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  6. Konstantinos Sinaniotis
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Correspondence to Dimitrios Doganis.

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Doganis, D., Mavrikou, M., Delis, D. et al. Timing of voiding cystourethrography in infants with first time urinary infection. Pediatr Nephrol 24, 319–322 (2009). https://doi.org/10.1007/s00467-008-1018-4

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  • DOI: https://doi.org/10.1007/s00467-008-1018-4

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