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Endoscopic ultrasound-guided transmural drainage for pancreatic fistula or pancreatic duct dilation after pancreatic surgery

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Abstract

Background

Endoscopic ultrasound (EUS)-guided drainage is widely used to manage pancreatic pseudocysts. Several studies have reported the use of EUS-guided drainage for pancreatic fistula and stasis of pancreatic juice caused by stricture of the pancreatic duct after pancreatic resection.

Methods

At the authors’ hospital, 262 patients underwent surgery involving pancreatic resection from April 2005 to March 2010. In 90 of these patients (34%), a grade B or C postoperative pancreatic fistula developed that required additional treatment. The authors performed EUS-guided transmural drainage (EUS-TD) for six patients (2.1%) with a pancreatic fistula or dilation of the main pancreatic duct visible by EUS. Percutaneous drainage was provided for 18 patients (6.8%). The success rates for EUS-TD and percutaneous drainage were compared in a retrospective analysis.

Results

In all six cases, EUS-TD was performed successfully without complications. Five of the six patients were successfully treated with only one trial of EUS-TD. The final technical success rate was 100% for both EUS-TD and percutaneous drainage. Both the short- and long-term clinical success rates for EUS-TD were 100% and those for percutaneous drainage were 61.1 and 83%, respectively. The differences in these rates were not significant (short-term success, P = 0.091 vs. long-term success, P = 0.403). However, the time to clinical success was significantly shorter with EUS-TD (5.8 days) than with percutaneous drainage (30.4 days; P = 0.0013) in the current series.

Conclusions

The EUS-TD approach appears to be a safe and technically feasible alternative to percutaneous drainage and may be considered as first-line therapy for pancreatic fistulas visible by EUS.

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Acknowledgments

We are deeply grateful to Professor Satoshi Kondo (formerly of the Department of Surgical Oncology, Hokkaido University Graduate School of Medicine), who provided support during the preparation of this article, but who passed away before its submission.

Disclosures

Manabu Onodera, Hiroshi Kawakami, Masaki Kuwatani, Taiki Kudo, Shin Haba, Yoko Abe, Shuhei Kawahata, Kazunori Eto, Yuya Nasu, Eiichi Tanaka, Satoshi Hirano, and Masahiro Asaka have no conflicts of interest or financial ties to disclose.

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Authors and Affiliations

  1. Department of Gastroenterology, Hokkaido University Graduate School of Medicine, Sapporo, 060-8638, Japan

    Manabu Onodera, Hiroshi Kawakami, Masaki Kuwatani, Taiki Kudo, Shin Haba, Yoko Abe, Shuhei Kawahata, Kazunori Eto & Masahiro Asaka

  2. Department of Surgical Oncology, Hokkaido University Graduate School of Medicine, Sapporo, 060-8638, Japan

    Yuya Nasu, Eiichi Tanaka & Satoshi Hirano

Authors
  1. Manabu Onodera
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  2. Hiroshi Kawakami
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Corresponding author

Correspondence to Hiroshi Kawakami.

Additional information

M. Onodera and H. Kawakami contributed equally to this work.

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Onodera, M., Kawakami, H., Kuwatani, M. et al. Endoscopic ultrasound-guided transmural drainage for pancreatic fistula or pancreatic duct dilation after pancreatic surgery. Surg Endosc 26, 1710–1717 (2012). https://doi.org/10.1007/s00464-011-2097-z

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  • DOI: https://doi.org/10.1007/s00464-011-2097-z

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