Abstract
Purpose
The use of transvaginal natural orifice transluminal endoscopic surgery (vNOTES) as the first choice of surgical route for patients scheduled to undergo conventional laparoscopy is still being debated. We aimed to evaluate and compare the outcomes of the “vNOTES first” strategy in benign gynecological cases.
Methods
All benign gynecological surgeries were initiated using vNOTES during the study period, regardless of the difficulty. Surgical outcomes, short-term patient satisfaction and sexual pain were compared between hysterectomies, adnexal and diagnostic procedures. Visual Analog Score (VAS), Patients Global Impressions of Improvements scale (PGI-I) and Female Sexual Function Index (FSFI) were used to assess the postoperative pain, satisfaction and sexual pain, respectively.
Results
A total of 105 vNOTES procedures were performed during the study period: 63 (60.58%) adnexal procedures, 36 (34.62%) hysterectomies, 5 (4.81%) diagnostic procedures and one (0.96%) myomectomy. The median 24th hour VAS scores for adnexal, hysterectomy, and diagnostic procedures were 1.29 ± 1.41, 2.06 ± 2.08, and 2.6 ± 2.41, respectively. The satisfaction rate was 96.19% at the 1st postoperative week and 97.14% at the first month. There was either no change or a slight improvement in the patients’ total score on the FSFI/pain domain before and after surgery. There were two conversions (1.9%) from vNOTES to laparoscopy and laparotomy, and two (5.56%) bladder injuries in hysterectomy cases.
Conclusion
Implementing the vNOTES technique as an initial approach for all benign gynecological surgeries seems feasible, safe and satisfactory, even in those with a non-prolapsed or enlarged uterus and those that have previously undergone abdominal surgery. The pain scores were found to be low and patients stated a high satisfaction with no or better change in their sexual life.
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Data availability
Data are available from the corresponding author on request.
References
Lee C-L, Wu K-Y, Su H, Ueng S-H, Yen C-F (2012) Transvaginal natural-orifice transluminal endoscopic surgery (NOTES) in adnexal procedures. J Minim Invasive Gynecol 19(4):509–513. https://doi.org/10.1016/j.jmig.2012.02.005
Kapurubandara S, Lowenstein L, Salvay H, Herijgers A, King J, Baekelandt J et al (2021) Consensus on safe implementation of vaginal natural orifice transluminal endoscopic surgery (vNOTES). Eur J Obstet Gynecol Reprod Biol 263:216–222. https://doi.org/10.1016/j.ejogrb.2021.06.019
Zakhari A, Papillon-Smith J, Mansour FW, Krishnamurthy S (2021) Transvaginal natural orifice transluminal endoscopic surgery (vNOTES) hysterectomy-first experiences at a canadian academic centre (2021). J Obstet Gynaecol Canada JOGC 43(12):1359–1360. https://doi.org/10.1016/j.jogc.2021.07.011
Chrysostomou A, Djokovic D, Edridge W, van Herendael BJ (2018) Evidence-based guidelines for vaginal hysterectomy of the International Society for Gynecologic Endoscopy (ISGE). Eur J Obstet Gynecol Reprod Biol 231:262–267. https://doi.org/10.1016/j.ejogrb.2018.10.058
Yassa M, Kaya C, Kalafat E, Tekin AB, Karakas S, Mutlu MA et al (2022) The comparison of transvaginal natural orifice transluminal endoscopic surgery and conventional laparoscopy in opportunistic bilateral sal**ectomy for permanent female sterilization. J Minim Invasive Gynecol 29(2):257–264. https://doi.org/10.1016/j.jmig.2021.08.009
Kaya C, Yıldız Ş, Alay İ, Karakaş S, Durmuş U, Güraslan H et al (2021) Comparison of surgical outcomes of total laparoscopic hysterectomy and vNOTES hysterectomy for undescended-enlarged uteri. J Investig Surg 2021:1–6. https://doi.org/10.1080/08941939.2021.1958111
Li C, Hua K (2020) Transvaginal natural orifice transluminal endoscopic surgery (vNOTES) in gynecologic surgeries: a systematic review. Asian J Surg 43(1):44–51. https://doi.org/10.1016/j.asjsur.2019.07.014
Bucher P, Ostermann S, Pugin F, Morel P (2011) Female population perception of conventional laparoscopy, transumbilical LESS, and transvaginal NOTES for cholecystectomy. Surg Endosc 25(7):2308–2315. https://doi.org/10.1007/s00464-010-1554-4
Mofid H, Emmermann A, Alm M, von Waldenfels H-A, Felixmüller C, Zornig C (2013) Is the transvaginal route appropriate for intra-abdominal NOTES procedures? Experience and follow-up of 222 cases. Surg Endosc 27(8):2807–2812. https://doi.org/10.1007/s00464-013-2812-z
Baekelandt JF, De Mulder PA, Le Roy I, Mathieu C, Laenen A, Enzlin P et al (2019) Hysterectomy by transvaginal natural orifice transluminal endoscopic surgery versus laparoscopy as a day-care procedure: a randomised controlled trial. BJOG An Int J Obstet Gynaecol 126(1):105–113. https://doi.org/10.1111/1471-0528.15504
Srikrishna S, Robinson D, Cardozo L (2010) Validation of the patient global impression of improvement (PGI-I) for urogenital prolapse. Int Urogynecol J 21(5):523–528. https://doi.org/10.1007/s00192-009-1069-5
Kaya C, Alay I, Cengiz H, Baghaki S, Aslan O, Ekin M et al (2021) Conventional laparoscopy or vaginally assisted natural orifice transluminal endoscopic surgery for adnexal pathologies: a paired sample cross-sectional study. J Investig Surg 234(11):1185–1190. https://doi.org/10.1080/08941939.2020.1789246
Kaya C, Alay I, Cengiz H, Yıldız GO, Baghaki HS, Yasar L (2021) Comparison of hysterectomy cases performed via conventional laparoscopy or vaginally assisted natural orifice transluminal endoscopic surgery: a paired sample cross-sectional study. J Obstet Gynaecol (Lahore) 41(3):434–438. https://doi.org/10.1080/01443615.2020.1741523
Gerntke CI, Kersten JF, Schön G, Mann O, Stark M, Benhidjeb T (2015) Women’s perception of transvaginal natural orifice transluminal endoscopic surgery (NOTES): results of a survey of female medical staff and literature review. Surg Innov 23(2):201–211. https://doi.org/10.1177/1553350615598621
Baekelandt J, Kapurubandara S (2021) Benign gynaecological procedures by vaginal natural orifice transluminal endoscopic surgery (vNOTES): complication data from a series of 1000 patients. Eur J Obstet Gynecol Reprod Biol 256:221–224. https://doi.org/10.1016/j.ejogrb.2020.10.059
Naval S (2022) vNOTES lateral window approach to hysterectomy in a case with previous history of multiple surgeries resulting in keloid scars and enlarged uterus with dense bladder adhesions. J Minim Invasive Gynecol 29(2):193. https://doi.org/10.1016/j.jmig.2021.08.020
Chrysostomou A, Djokovic D, Edridge W, van Herendael BJ (2020) Evidence-based practical guidelines of the International Society for Gynecologic Endoscopy (ISGE) for vaginal hysterectomy. Eur J Obstet Gynecol Reprod Biol 252:118–126. https://doi.org/10.1016/j.ejogrb.2020.06.027
Buzzaccarini G, Stabile G, Török P, Petousis S, Mikuš M, Della Corte L et al (2022) Surgical approach for enlarged uteri: further tailoring of vNOTES hysterectomy. J Investig Surg 35(4):924–925. https://doi.org/10.1080/08941939.2021.1967528
Wang C-J, Huang H-Y, Huang C-Y, Su H (2015) Hysterectomy via transvaginal natural orifice transluminal endoscopic surgery for nonprolapsed uteri. Surg Endosc 29(1):100–107. https://doi.org/10.1007/s00464-014-3639-y
Yang YS, Kim SY, Hur MH, Oh KY (2014) Natural orifice transluminal endoscopic surgery-assisted versus single-port laparoscopic-assisted vaginal hysterectomy: a case-matched study. J Minim Invasive Gynecol 21(4):624–631. https://doi.org/10.1016/j.jmig.2014.01.005
Kim SH, ** CH, Hwang IT, Park JS, Shin JH, Kim DW et al (2018) Postoperative outcomes of natural orifice transluminal endoscopic surgery-assisted vaginal hysterectomy and conventional laparoscopic-assisted vaginal hysterectomy: a comparative study. Obstet Gynecol Sci 61(2):261–266. https://doi.org/10.5468/ogs.2018.61.2.261
Karakaş S, Kaya C, Yildiz Ş, Alay İ, Durmuş U, Aydiner İE et al (2022) Comparison of vNOTES technique with conventional laparoscopy in gynecological emergency cases. Minim Invasive Ther Allied Technol. https://doi.org/10.1080/13645706.2021.2025111
Ozceltik G, Simsek D, Hortu I, Yeniel AO, Itil IM (2022) Transvaginal natural orifice transluminal endoscopic surgery for ectopic pregnancy. J Obstet Gynaecol Res 48(3):843–849. https://doi.org/10.1111/jog.15165
Varlas V, Rhazi Y, Cloțea E, Borș RG, Mirică RM, Bacalbașa N (2021) Hysterolaparoscopy: a gold standard for diagnosing and treating infertility and benign uterine pathology. J Clin Med 10(16):3749. https://doi.org/10.3390/jcm10163749
Baekelandt J (2018) Transvaginal natural-orifice transluminal endoscopic surgery: a new approach to myomectomy. Fertil Steril 109(1):179. https://doi.org/10.1016/j.fertnstert.2017.09.009
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All authors contributed to the study conception and design. Material preparation, data collection and analysis were performed by ABT, MY, DB, Pinar BI, MAM, EY, OSG and NT. The first draft of the manuscript was written by ABT, MY, CK, CU, NT and all authors commented on previous versions of the manuscript. All authors read and approved the final manuscript.
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Tekin, A.B., Yassa, M., Kaya, C. et al. Implementing the transvaginal natural orifice transluminal endoscopic surgery (vNOTES) “first” strategy in benign gynecological surgeries. Arch Gynecol Obstet 307, 1007–1013 (2023). https://doi.org/10.1007/s00404-022-06859-9
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DOI: https://doi.org/10.1007/s00404-022-06859-9