Abstract
Intracranial mature teratomas have good prognoses and are usually treated by total tumor resection. We report a rare case of a germinoma that occurred 11 years after total removal of a pineal mature teratoma. A 5-year-old boy presented with headache and nausea and was diagnosed with a pineal tumor and obstructive hydrocephalus on MRI. He underwent total removal of the lesion, which was pathologically diagnosed as a mature teratoma without any other germ cell tumor components. MR images after 11 years showed a newly developed pineal tumor, which was confirmed as a germinoma after neuroendoscopic biopsy. Chemoradiotherapy resulted in complete remission, without any symptoms. This case demonstrated possible late occurrence of germinoma even after total removal of a mature teratoma had been achieved. A long-term follow-up of 10 years or more should be planned for these patients.
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Acknowledgments
The authors would like to thank Dr. Noriaki Sakamoto for preparing the histopathology photo. We would like to thank Editage (www.editage.com) for English language editing.
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This study did not receive any specific grant from funding agencies in the public, commercial, or not-for-profit sectors.
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Sakakura, K., Muroi, A., Tsurubuchi, T. et al. Pure germinoma occurring 11 years after total pineal mature teratoma removal: a case report and review of the literature. Childs Nerv Syst 35, 2423–2426 (2019). https://doi.org/10.1007/s00381-019-04332-8
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DOI: https://doi.org/10.1007/s00381-019-04332-8