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Total-body contrast-enhanced MRA on a short, wide-bore 1.5-T system: intra-individual comparison of Gd-BOPTA and Gd-DOTA

  • Magnetic Resonance
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Abstract

Total-body contrast-enhanced MRA (CE-MRA) provides information of the entire vascular system according to a one-stop-shop approach. Short, wide-bore scanners have not yet been used for total-body CE-MRA, probably due to their restricted field of view in the z-direction. The purpose of this feasibility study is to introduce an image protocol for total-body MRA on a short, wide-bore system. The protocol includes five to six table-moving steps and two injection runs. Two pharmacologically different contrast materials (CM) were applied in ten healthy volunteers in view of possible CM-dependent influences on the protocol outcome (Gd-Bopta, Gd-Dota). Differences consisted of significantly higher CNR with Gd-Bopta with a mean of 73.8 ± 38.7 versus 69.1 ± 34.3 (p = 0.008), significantly better arterial visualization values with Gd-Dota with a mean of 1.26 ± 0.44 versus 1.53 ± 0.73 (p = 0.003) and a tendency to less venous overlay with Gd-Dota, mean 1.19 ± 0.44 and 1.34 ± 0.72, respectively (p = 0.065) (two-tailed Wilcoxon matched-pairs test). Overall 94% of the steps were valued as qualitatively excellent or good. The good results with both CM suggest a transfer to further patient evaluation.

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Acknowledgement

We thank Tanja Haas and Philipp Madoerin for their great support for MR scanning and image preparation.

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Authors and Affiliations

  1. Department of Radiology, University Hospital Basel, Petersgraben 4, 4031, Basel, Switzerland

    M. Rasmus, J. Bremerich, T. Egelhof, R. W. Huegli, G. Bongartz & D. Bilecen

  2. Department of Radiology, Kantonsspital Bruderholz, 4101, Bruderholz, Switzerland

    R. W. Huegli

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  1. M. Rasmus
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  2. J. Bremerich
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  3. T. Egelhof
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  4. R. W. Huegli
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  5. G. Bongartz
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  6. D. Bilecen
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Correspondence to M. Rasmus.

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Rasmus, M., Bremerich, J., Egelhof, T. et al. Total-body contrast-enhanced MRA on a short, wide-bore 1.5-T system: intra-individual comparison of Gd-BOPTA and Gd-DOTA. Eur Radiol 18, 2265–2273 (2008). https://doi.org/10.1007/s00330-008-0976-z

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  • DOI: https://doi.org/10.1007/s00330-008-0976-z

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