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Polymyalgia rheumatica in primary Sjögren’s syndrome

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Abstract

The aim of the study was to describe the clinical and laboratory aspects of primary Sjögren’s syndrome (pSS) associated with polymyalgia rheumatica (PMR). The retrospective study compares the clinical and laboratory aspects of patients with pSS associated with PMR on a relatively large cohort of patients (n=16) and pSS patients without PMR (n=531). The prevalence of PMR among pSS patients was 3%, while in the average population, the prevalence of PMR is only 0.75%. PMR developed 8.7 years after the diagnosis of pSS in the older female pSS population (over 50 years of age), and in those with only glandular features. Interestingly the pSS/PMR patients had hypo gammaglobuline levels, while in the pSS patient group hypergammaglobulinaemia presented. Furthermore, positive ANA serology was more frequent among pSS/PMR patients. Since the clinical management of pSS/PMR is different from pSS, a better understanding of this clinical entity is essential.

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Authors and Affiliations

  1. Broegelmann Research Laboratory, The Gade Institute, University of Bergen, Armauer Hansen Bldg, 5021, Bergen, Norway

    Peter Szodoray & Roland Jonsson

  2. Department of Rheumatology, Haukeland University Hospital, University of Bergen, Bergen, Norway

    Johan G. Brun

  3. Division of Clinical Immunology, 3rd Department of Medicine, Medical and Health Science Center, University of Debrecen, Debrecen, Hungary

    Margit Zeher

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  1. Peter Szodoray
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  2. Roland Jonsson
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  3. Johan G. Brun
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  4. Margit Zeher
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Correspondence to Peter Szodoray.

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Szodoray, P., Jonsson, R., Brun, J.G. et al. Polymyalgia rheumatica in primary Sjögren’s syndrome. Rheumatol Int 26, 401–403 (2006). https://doi.org/10.1007/s00296-005-0010-6

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  • DOI: https://doi.org/10.1007/s00296-005-0010-6

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