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Primary transplantation of allogeneic peripheral blood stem cell for severe aplastic anemia

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Abstract

 Primary allogeneic peripheral blood stem cell transplantation (allo-PBSCT) has not been previously described in the treatment of severe aplastic anemia (SAA). We report a patient with SAA who underwent primary allo-PBSCT with cells from her HLA-identical sibling and achieved rapid bone marrow reconstitution. The patient has been in complete remission with normal blood counts for 9 months following allo-PBSCT. This suggests that primary allo-PBSCT is a safe and effective alternative in the treatment of SAA.

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Authors and Affiliations

  1. Division of Hematology, Department of Medicine, Veterans General Hospital-Taipei and National Yang-Ming University, Shih-pai, Taipei, Taiwan 11217, Republic of China, , , , , , TW

    H. C. Hsu, W. H. Tsai & C. H. Ho

  2. Department of Medical Research, Veterans General Hospital-Taipei and National Yang-Ming University, Taipei, Taiwan, Republic of China, , , , , , TW

    S. Y. Wang

  3. Division of Transfusion Medicine, Department of Medicine, Veterans General Hospital-Taipei and National Yang-Ming University, Taipei, Taiwan, Republic of China, , , , , , TW

    J. S. Lin & C. H. Tzeng

Authors
  1. H. C. Hsu
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  2. W. H. Tsai
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  3. J. S. Lin
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  4. C. H. Tzeng
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  5. S. Y. Wang
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  6. C. H. Ho
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Additional information

Received: 13 November 1996 / Accepted: 29 January 1997

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Hsu, H., Tsai, W., Lin, J. et al. Primary transplantation of allogeneic peripheral blood stem cell for severe aplastic anemia. Ann Hematol 74, 191–192 (1997). https://doi.org/10.1007/s002770050281

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  • DOI: https://doi.org/10.1007/s002770050281

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