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Radiofrequency Ablation in Combination with Embolization in Metachronous Recurrent Renal Cancer in Solitary Kidney after Contralateral Tumor Nephrectomy

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Abstract

Purpose

To evaluate the feasibility and safety of minimally invasive, percutaneous techniques in metachronous recurrent renal cell cancers (RCCs) in solitary kidneys.

Methods

In 4 patients, recurrent RCC was treated by radiofrequency ablation (RFA) (RITA, StarBurst) alone, and in 2 patients by RFA in combination with superselective transarterial particle-lipiodol embolization using 3 Fr microcatheters. RFA was guided by computed tomography in 5 patients, and by magnetic resonance imaging in 1 patient. Mean tumor diameter was 26.7 mm (range 10–45 mm). All interventions were technically successful; during follow-up 1 patient developed recurrent RCC, which was retreated by RFA after embolization.

Results

No major peri- or postprocedural complications occurred. Changes in creatinine (pre- vs. post-intervention, 122 vs. 127 μmol/l) and calculated creatinine clearance (pre- vs. post-intervention, 78 vs. 73 ml/min) after ablation were minimal.

Conclusion

In single kidneys, percutaneous, minimally invasive techniques are safe and feasible. In large tumors, or where there are adjacent critical structures, we prefer a combination of embolization and thermal ablation (RFA).

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Authors and Affiliations

  1. Department of Radiology, Charité, Universitätsmedizin Berlin Campus Virchow-Clinic, Augustenburger Platz 1, 13353, Berlin, Germany

    Bernhard Gebauer, Michael Werk, Enrique Lopez-Hänninen & Roland Felix

  2. Department of Urology, Evangelisches Krankenhaus Königin Elisabeth Herzberge, Herzberg Strasse 79, 10365, Berlin, Germany

    Peter Althaus

Authors
  1. Bernhard Gebauer
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  2. Michael Werk
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  3. Enrique Lopez-Hänninen
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  4. Roland Felix
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  5. Peter Althaus
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Correspondence to Bernhard Gebauer.

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Gebauer, B., Werk, M., Lopez-Hänninen, E. et al. Radiofrequency Ablation in Combination with Embolization in Metachronous Recurrent Renal Cancer in Solitary Kidney after Contralateral Tumor Nephrectomy. Cardiovasc Intervent Radiol 30, 644–649 (2007). https://doi.org/10.1007/s00270-007-9012-y

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