Abstract
Endometriosis is a common condition with significant morbidity, including pain and subfertility, which is often subject to a delay in diagnosis. Ultrasound has been successfully utilized, mostly outside North America, to preoperatively stage deep endometriosis, but in these international settings, imaging is typically performed solely by expert radiologists and gynecologists. We outline a method for detailed sonographic survey of the lower abdomen and pelvis to ensure optimum detection and communication of disease extent that is geared to radiologists practicing ultrasound in the United States, with the use of diagnostic medical sonographers.
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References
Eskenazi B, Warner ML (1997) Epidemiology of endometriosis. Obstet Gynecol Clin N Am 24(2):235–258
Schliep KC, et al. (2015) Pain typology and incident endometriosis. Human Reprod 30(10):2427–2438
Holland TK, et al. (2013) Ultrasound map** of pelvic endometriosis: does the location and number of lesions affect the diagnostic accuracy? A multicentre diagnostic accuracy study. BMC women health 13:43
Reid S, et al. (2013) Prediction of pouch of Douglas obliteration in women with suspected endometriosis using a new real-time dynamic transvaginal ultrasound technique: the sliding sign. Ultrasound Obstet Gynecol 41(6):685–691
Reid S, et al. (2014) Office gel sonovaginography for the prediction of posterior deep infiltrating endometriosis: a multicenter prospective observational study. Ultrasound Obstet Gynecol 44(6):710–718
Hudelist G, et al. (2013) Uterine sliding sign: a simple sonographic predictor for presence of deep infiltrating endometriosis of the rectum. Ultrasound Obstet Gynecol 41(6):692–695
Exacoustos C, et al. (2014) Ultrasound map** system for the surgical management of deep infiltrating endometriosis. Fertil Steril 102(1):143–150
Goncalves MO, et al. (2010) Transvaginal ultrasonography with bowel preparation is able to predict the number of lesions and rectosigmoid layers affected in cases of deep endometriosis, defining surgical strategy. Human Rep 25(3):665–671
Nnoaham KE, et al. (2011) Impact of endometriosis on quality of life and work productivity: a multicenter study across ten countries. Fertil Steril 96(2):366–373
Doniec JM, et al. (2003) Rectal endometriosis: high sensitivity and specificity of endorectal ultrasound with an impact for the operative management. Dis Colon Rectum 46(12):1667–1673
Chapron C, Dubuisson JB (2001) Management of deep endometriosis. Ann N Y Acad Sci 943:276–280
Garry R, Clayton R, Hawe J (2000) The effect of endometriosis and its radical laparoscopic excision on quality of life indicators. Int J Obstet Gynaecol 107(1):44–54
Coccia ME, Rizzello F (2011) Ultrasonographic staging: a new staging system for deep endometriosis. Ann N Y Acad Sci 1221:61–69
Noventa M, et al. (2015) Ultrasound techniques in the diagnosis of deep pelvic endometriosis: algorithm based on a systematic review and meta-analysis. Fertil Steril 104(2):366–383
Cornillie FJ, et al. (1990) Deeply infiltrating pelvic endometriosis: histology and clinical significance. Fertil Steril 53(6):978–983
Nisolle M, Donnez J (1997) Peritoneal endometriosis, ovarian endometriosis, and adenomyotic nodules of the rectovaginal septum are three different entities. Fertil Steril 68(4):585–596
Giudice LC, Kao LC (2004) Endometriosis. Lancet 364(9447):1789–1799
Hudelist G, et al. (2009) Combination of transvaginal sonography and clinical examination for preoperative diagnosis of pelvic endometriosis. Human Reprod 24(5):1018–1024
Leon M, et al. (2014) Extended transvaginal sonography in deep infiltrating endometriosis: use of bowel preparation and an acoustic window with intravaginal gel: preliminary results. J Ultrasound Med 33(2):315–321
Benacerraf BR, et al. (2015) Deep infiltrating endometriosis of the bowel wall: the comet sign. J Ultrasound Med 34(3):537–542
Abrao MS, et al. (2007) Comparison between clinical examination, transvaginal sonography and magnetic resonance imaging for the diagnosis of deep endometriosis. Human Rep 22(12):3092–3097
Guerriero S, et al. (2015) Accuracy of transvaginal ultrasound for diagnosis of deep endometriosis in uterosacral ligaments, rectovaginal septum, vagina and bladder: systematic review and meta-analysis. Ultrasound Obstet Gynecol 46(5):534–545
Chapron C, et al. (2010) Surgery for bladder endometriosis: long-term results and concomitant management of associated posterior deep lesions. Human Reprod 25(4):884–889
Hudelist G, et al. (2009) Can transvaginal sonography predict infiltration depth in patients with deep infiltrating endometriosis of the rectum? Human Reprod 24(5):1012–1017
Bazot, M., et al., Diagnostic accuracy of transvaginal sonography for deep pelvic endometriosis. Ultrasound Obstet Gynecol 24(2):180–185
Del Frate C, et al. (2006) Deep retroperitoneal pelvic endometriosis: MR imaging appearance with laparoscopic correlation. Radiographics 26(6):1705–1718
Chapron C, et al. (2003) Anatomical distribution of deeply infiltrating endometriosis: surgical implications and proposition for a classification. Human Reprod 18(1):157–161
Pateman K, et al. (2015) Should a detailed ultrasound examination of the complete urinary tract be routinely performed in women with suspected pelvic endometriosis? Human Reprod 30(12):2802–2807
Balthazar EJ (2000) Diseases of the appendix. In: Gore RM, Levine MS (eds) Textbook of gastrointestinal radiology. Philadelphia: W. B. Saunders Company, pp 1123–1150
Willekens I, et al. (2014) The normal appendix on CT: does size matter? PloS One 9(5):e96476
Di Donato N, et al. (2014) Prevalence of adenomyosis in women undergoing surgery for endometriosis. Eur J Obstet Gynecol Reprod Biol 181:289–293
Abrao MS, et al. (2008) Endometriosis lesions that compromise the rectum deeper than the inner muscularis layer have more than 40% of the circumference of the rectum affected by the disease. J Minim Invasive Gynecol 15(3):280–285
Wolthuis AM, et al. (2014) Bowel endometriosis: colorectal surgeon’s perspective in a multidisciplinary surgical team. World J Gastroenterol 20(42):15616–15623
Kondo W, et al. (2015) Laparoscopic double discoid resection with a circular stapler for bowel endometriosis. J Minim Invasive Gynecol 22(6):929–931
Darwish B, Roman H (2016) Surgical treatment of deep infiltrating rectal endometriosis: in favor of less aggressive surgery. Am J Obstet Gynecol 215(2):195–200
Haber HP, Stern M (2000) Intestinal ultrasonography in children and young adults: bowel wall thickness is age dependent. J Ultrasound Med 19(5):315–321
Koga K, et al. (2003) Characteristic images of deeply infiltrating rectosigmoid endometriosis on transvaginal and transrectal ultrasonography. Human Reprod 18(6):1328–1333
Ferreira MC, Carneiro MM (2010) Ultrasonographic aspects of endometriosis. J Endometr 2(2):47–54
Massein A, et al. (2013) Imaging of intestinal involvement in endometriosis. Diagn interv Imaging 94(3):281–291
Abrao MS (2012) Surgical management of deep infiltrating endometriosis. Int J Gynecol Obstet 119(Suppl 3):S161
Acknowledgments
The authors acknowledge Drs. Manoel Gonçalves, Mauricio Abrão and Leandro Accardo de Mattos at Clinica Medicina da Mulher in São Paolo, Brazil for their invaluable training.
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261_2016_886_MOESM1_ESM.avi
Video 1: Uterine sliding sign, normal appearance. The transducer is seated in the anterior fornix, just in front of the anterior cervical lip, adjacent to the urinary bladder. Note the sharp, smooth interface between the posterior wall of the cervix and the bowel and retrocervical adipose deep to the cervix and uterine body. Free motion is evident during ballottement (AVI 9067 KB).
261_2016_886_MOESM2_ESM.avi
Video 2: Uterine sliding sign, abnormal appearance. Note the irregular, hypoechoic interface between the cervix and retrocervical/rectal endometriotic implant. Findings are consistent with posterior cul-de-sac obliteration “frozen pelvis” (AVI 9026 KB).
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Young, S.W., Saphier, N.B., Dahiya, N. et al. Sonographic evaluation of deep endometriosis: protocol for a US radiology practice. Abdom Radiol 41, 2364–2379 (2016). https://doi.org/10.1007/s00261-016-0886-5
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DOI: https://doi.org/10.1007/s00261-016-0886-5