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Primary cardiac tumors associated with genetic syndromes: a comprehensive review

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Abstract

Various cardiac tumors occur in the setting of a genetic syndrome such as myxomas in Carney complex and rhabdomyomas in tuberous sclerosis. Tumor biology can be different in syndromic forms, and on imaging children sometimes demonstrate additional manifestations of the underlying syndrome. We discuss the imaging appearance of cardiac tumors occurring in the framework of a genetic syndrome, the findings that suggest an underlying syndrome, and the impact on management.

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Authors and Affiliations

  1. Division of Cardiothoracic Radiology, Department of Radiology, University of Michigan Health System, University Hospital Floor B1 Reception C, 1500 E. Medical Center Drive SPC 5030, Ann Arbor, MI, 48109, USA

    Elizabeth Lee, Maryam Ghadimi Mahani & Prachi P. Agarwal

  2. Section of Pediatric Radiology, C. S. Mott Children’s Hospital, Department of Radiology, University of Michigan Health System, Ann Arbor, MI, USA

    Maryam Ghadimi Mahani, Jimmy C. Lu & Adam L. Dorfman

  3. Section of Pediatric Cardiology, Department of Pediatrics, C. S. Mott Children’s Hospital, University of Michigan Health System, Ann Arbor, MI, USA

    Jimmy C. Lu & Adam L. Dorfman

  4. Division of Neuroradiology, Department of Radiology, University of Michigan Health System, Ann Arbor, MI, USA

    Ashok Srinivasan

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  1. Elizabeth Lee
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  2. Maryam Ghadimi Mahani
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Correspondence to Elizabeth Lee.

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Lee, E., Mahani, M.G., Lu, J.C. et al. Primary cardiac tumors associated with genetic syndromes: a comprehensive review. Pediatr Radiol 48, 156–164 (2018). https://doi.org/10.1007/s00247-017-4027-2

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  • DOI: https://doi.org/10.1007/s00247-017-4027-2

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