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Lipofilling in Rahmen der Mammachirurgie

Ergebnisse einer retrospektiven Analyse

Autologous fat grafting in breast surgery

Results of a retrospective study

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Zusammenfassung

Hintergrund

Die autologe Fettgewebstransplantation, auch als Lipofilling bezeichnet, besitzt als körpereigenes Gewebe die Eigenschaften eines idealen Fillers. Sie wird in der rekonstruktiven und ästhetischen Chirurgie zur Korrektur angeborener oder erworbener Weichteildeformitäten insbesondere der Brust angewendet.

Methodik

Von Mai 2007 bis September 2012 wurden 298 autologe Fettgewebstransplantationen bei 199 Patienten durchgeführt. Die Hauptindikation waren Konturdeformitäten und Volumenverlust nach Brustkrebsoperationen bzw. Brustfehlbildungen wie Asymmetrie, Hypoplasie, Poland-Syndrom oder tubuläre Brust. Das Fett wurde mit dem Tissue-Trans™ (Shippert Medical), Lipivage™ (Polytech) oder einem selbst entwickelten Sammelsystem gewonnen und unmittelbar ohne weitere Aufbereitung subkutan bzw. intramuskulär reinjiziert.

Ergebnisse

Das mittlere Patientenalter lag bei 45 Jahren. Meist wurden eine (42 %) oder zwei (31 %) Behandlungen durchgeführt. Das pro Operation im Durchschnitt transplantierte Volumen betrug 90 ml. In 2 % der Fälle trat eine lokale Infektion auf, die antibiotisch behandelt wurde.

Schlussfolgerung

Lipofilling ist eine einfache, schnelle, komplikationsarme und effektive Behandlungsmethode und somit eine wichtige Therapieergänzung bei Brustfehlbildungen und -deformitäten. Man erreicht nicht nur eine schönere Kontur und ein größeres Volumen, es zeigt sich auch eine Verbesserung der Narbenqualität.

Abstract

Background

Autologous fat has many qualities for an ideal filler and is widely used in reconstructive and aesthetic surgery, especially in the treatment of primary and secondary deformities of the breast.

Methods

From May 2007 to September 2012 298 autologous fat graftings were performed in 199 patients. Fat was harvested using the Tissue-Trans™ (Shippert Medical), Lipivage™ (Polytech) or a self-developed harvesting system and injected without any further processing into subcutaneous and/or intramuscular layers.

Results

The mean patient age was 45 years. Main indications were contour deformities and volume loss after breast cancer surgery as well as asymmetry, hypoplasia, Poland syndrome or tuberous breasts. The average volume of grafted fat was 90 ml per surgery. Most patients received one (42 %) or two (31 %) sessions of treatment. The infection rate was 2 % which was further treated with oral antibiotics.

Conclusion

Autologous fat grafting represents an important tool for the management of deformities of the breast not only by filling deformities and adding volume, but also by improving the quality of scars. It is a simple, fast and effective treatment option with few complications.

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Literatur

  1. Berry MG, Stanek JJ (2014) PIP silicone breast implants. J Plast Reconstr Aesthet Surg 67:127–128

    Article  CAS  PubMed  Google Scholar 

  2. Pienaar WE, McWilliams S, Wilding LJ, Perera IT (2011) The imaging features of MACROLANE in breast augmentation. Clin Radiol 66:977–983

    Article  CAS  PubMed  Google Scholar 

  3. Bircoll M, Novack BH (1987) Autologous fat transplantation employing liposuction techniques. Ann Plast Surg 18:327–329

    Article  CAS  PubMed  Google Scholar 

  4. Coleman SR, Saboeiro AP (2007) Fat grafting to the breast revisited: safety and efficacy. Plast Reconstr Surg 119:775–785 (discussion 786–777)

    Article  CAS  PubMed  Google Scholar 

  5. Delay E, Garson S, Tousson G, Sinna R (2009) Fat injection to the breast: technique, results, and indications based on 880 procedures over 10 years. Aesthet Surg J 29:360–376

    Article  PubMed  Google Scholar 

  6. Rigotti G, Marchi A, Galie M et al (2007) Clinical treatment of radiotherapy tissue damage by lipoaspirate transplant: a healing process mediated by adipose-derived adult stem cells. Plast Reconstr Surg 119:1409–1422 (discussion 1423–1404)

    Article  CAS  PubMed  Google Scholar 

  7. Pu LL, Coleman SR, Cui X et al (2008) Autologous fat grafts harvested and refined by the Coleman technique: a comparative study. Plast Reconstr Surg 122:932–937

    Article  CAS  PubMed  Google Scholar 

  8. Smith P, Adams WP Jr, Lipschitz AH et al (2006) Autologous human fat grafting: effect of harvesting and preparation techniques on adipocyte graft survival. Plast Reconstr Surg 117:1836–1844

    Article  CAS  PubMed  Google Scholar 

  9. Kirkham JC, Lee JH, Medina MA III et al (2012) The impact of liposuction cannula size on adipocyte viability. Ann Plast Surg 69:479–481

    Article  CAS  PubMed  Google Scholar 

  10. Ferguson RE, Cui X, Fink BF et al (2008) The viability of autologous fat grafts harvested with the LipiVage system: a comparative study. Ann Plast Surg 60:594–597

    Article  CAS  PubMed  Google Scholar 

  11. Agostini T, Lazzeri D, Pini A et al (2012) Wet and dry techniques for structural fat graft harvesting: histomorphometric and cell viability assessments of lipoaspirated samples. Plast Reconstr Surg 130:331e–339e

    Article  CAS  PubMed  Google Scholar 

  12. Coleman SR (2006) Structural fat grafting: more than a permanent filler. Plast Reconstr Surg 118:108s–120s

    Article  CAS  PubMed  Google Scholar 

  13. Lee JH, Kirkham JC, McCormack MC et al (2013) The effect of pressure and shear on autologous fat grafting. Plast Reconstr Surg 131:1125–1136

    Article  CAS  PubMed  Google Scholar 

  14. Kolle SF, Fischer-Nielsen A, Mathiasen AB et al (2013) Enrichment of autologous fat grafts with ex-vivo expanded adipose tissue-derived stem cells for graft survival: a randomised placebo-controlled trial. Lancet 382:1113–1120

    Article  PubMed  Google Scholar 

  15. Chajchir A, Benzaquen I, Wexler E, Arellano A (1990) Fat injection. Aesthetic Plast Surg 14:127–136

    Article  CAS  PubMed  Google Scholar 

  16. Coleman SR (2001) Structural fat grafts: the ideal filler? Clin Plast Surg 28:111–119

    CAS  PubMed  Google Scholar 

  17. Claro F Jr, Figueiredo JC, Zampar AG, Pinto-Neto AM (2012) Applicability and safety of autologous fat for reconstruction of the breast. Br J Surg 99:768–780

    Article  PubMed  Google Scholar 

  18. Vallejo A, Urban C, Zucca-Matthes G, Rietjens M (2013) Is there enough evidence to use lipofilling in breast cancer reconstruction? Plast Reconstr Surg 132:689e–691e

    Article  PubMed  Google Scholar 

  19. Largoa RD, Häcki J, Güven S et al (2011) Autologe Fetttransplantation in die weibliche Brust. Klinische Anwendung und Sicherheitsaspekte. Schweiz Med Forum 11:489–494

    Google Scholar 

  20. Petit JY, Rietjens M, Botteri E et al (2013) Evaluation of fat grafting safety in patients with intraepithelial neoplasia: a matched-cohort study. Ann Oncol 24:1479–1484

    Article  CAS  PubMed  Google Scholar 

  21. Krastev TK, Jonasse Y, Kon M (2013) Oncological safety of autologous lipoaspirate grafting in breast cancer patients: a systematic review. Ann Surg Oncol 20:111–119

    Article  CAS  PubMed  Google Scholar 

  22. Losken A, Pinell XA, Sikoro K et al (2011) Autologous fat grafting in secondary breast reconstruction. Ann Plast Surg 66:518–522

    Article  CAS  PubMed  Google Scholar 

  23. Rietjens M, De Lorenzi F, Rossetto F et al (2011) Safety of fat grafting in secondary breast reconstruction after cancer. J Plast Reconstr Aesthet Surg 64:477–483

    Article  CAS  PubMed  Google Scholar 

  24. Serra-Renom JM M-OJ, Serra-Mestre JM (2011) Breast reconstruction with fat grafting alone. Ann Plast Surg 66(66):598–601

    Article  CAS  PubMed  Google Scholar 

  25. Khouri RK, Eisenmann-Klein M, Cardoso E et al (2012) Brava and autologous fat transfer is a safe and effective breast augmentation alternative: results of a 6-year, 81-patient, prospective multicenter study. Plast Reconstr Surg 129:1173–1187

    Article  CAS  PubMed  Google Scholar 

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Einhaltung ethischer Richtlinien

Interessenkonflikt. E. Russe, T. Schöller, H. Hussl, P. Pülzl, H. Reichl, F. Ensat, M. Hladik und G. Wechselberger geben an, dass kein Interessenkonflikt besteht. Dieser Beitrag beinhaltet keine Studien an Menschen oder Tieren.

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Russe, E., Schöller, T., Hussl, H. et al. Lipofilling in Rahmen der Mammachirurgie. Chirurg 86, 476–481 (2015). https://doi.org/10.1007/s00104-014-2775-1

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  • DOI: https://doi.org/10.1007/s00104-014-2775-1

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