References
Oda T, Morikawa N, Saito Y, Masuho Y, Matsumoto S. Molecular cloning and characterization of a novel type of histamine receptor preferentially expressed in leukocytes. J Biol Chem. 2000;275:36781–6.
Nguyen T, Shapiro DA, George SR, Setola V, Lee DK, Cheng R, et al. Discovery of a novel member of the histamine receptor family. Mol Pharmacol. 2001;59:427–33.
Thurmond RL, Gelfand EW, Dunford PJ. The role of histamine H1 and H4 receptors in allergic inflammation: the search for new antihistamines. Nat Rev Drug Discov. 2008;7(1):41–53.
Zampeli E, Tiligada E. The role of histamine H4 receptor in immune and inflammatory disorders. Br J Pharmacol. 2009;157:24–33.
Thurmond RL, Desai PJ, Dunford PJ, Fung-Leung WP, Hofstra CL, Jiang W, et al. A potent and selective histamine H4 receptor antagonist with anti-inflammatory properties. J Pharmacol Exp Ther. 2004;309:404–13.
Schneider EH, Schnell D, Papa D, Seifert R. High constitutive activity and a G protein-independent high-affinity state of the human histamine H4 receptor. Biochemistry. 2009;48:1424–38.
Acknowledgments
Partly supported by the Ministry of Scientific Research and Information Technology, Poland grant no. DAAD/55/2007. Authors are affiliated with COST Action BM0806.
Author information
Authors and Affiliations
Corresponding author
Rights and permissions
About this article
Cite this article
Karcz, T., Handzlik, J., Łażewska, D. et al. Search for histamine H4 receptor ligands in the group of 4-methylpiperazino amide derivatives. Inflamm. Res. 59 (Suppl 2), 243–245 (2010). https://doi.org/10.1007/s00011-009-0141-4
Published:
Issue Date:
DOI: https://doi.org/10.1007/s00011-009-0141-4