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Viral hepatitis (HBV and HCV) background in Chinese patients with hepatocellular carcinoma

  • The Paper Symposium On PLC
  • Published:
Chinese Journal of Cancer Research

Abstract

Antibody to hepatitis C virus (Anti-HCV) was detected using anti-HCV EIA (Abbott Kit) in the sera of Chinese patients with hepatocellular carcinoma (HCC), acute hepatitis, chronic hepatitis and blood donors, the positive rates being 10.4% (61/586), 11.8% (10/85), 19.2% (44/229), and 1.9% (3/160) respectively. HBV DNA was detected by polymerase chain reaction (PCR) in sera from 61 HCC patients with positive anti-HCV, the positive rate for HBV DNA being 55.7% (34/61), which was lower than those with negative anti-HCV (78.7%, 413/525). These results indicate that in China the role of HBV infection in the causation of HCC seems to be more important than that of HCV infection.

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Authors and Affiliations

  1. Liver Cancer Institute, Shanghai Medical University, 200032, Shanghai

    Yu Zhuyuan, Tang Zhaoyou, Yang Binghui & Lawrence Lumeng

  2. Division of Gastroenterdogy/Hepatology, Indiana University Medical Center, 46223, Indianapolis, Indiana, USA

    Lawrence Lumeng

Authors
  1. Yu Zhuyuan
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  2. Tang Zhaoyou
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  3. Yang Binghui
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  4. Lawrence Lumeng
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Additional information

This paper is one of the symposium papers on primary liver cancer research (Chin J Cancer Res 6(1), 1994)

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Yu, Z., Tang, Z., Yang, B. et al. Viral hepatitis (HBV and HCV) background in Chinese patients with hepatocellular carcinoma. Chin J Cancer Res 6, 79–82 (1994). https://doi.org/10.1007/BF02997239

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  • DOI: https://doi.org/10.1007/BF02997239

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