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Some aspects of the molecular pathology of thrombosis and haemorrhage

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References

  • Castellino, F. J. 1979. A unique enzyme-protein substrate modified reaction: plasmin/streptokinase interaction. Trends in Biochemical Science 4, 1–5.

    Article  CAS  Google Scholar 

  • Cederholm-Williams, S. and Fennell, S. J. 1981. Binding of plasmin(ogen) to Sepharose bound fibrin(ogen) α chain. Thrombos. Res. 21, 503- 504.

    Article  CAS  Google Scholar 

  • Chesterman, C. N. 1978. Fibrinolysis and disseminated intravascular coagulation. In: Fibrinolysis: Current Fundamental and Clinical Concepts. Eds. P. J. Gaffney and S. Balkuv-Ulutin. Academic Press, London, pp. 157–172.

    Google Scholar 

  • Collen, D. 1976. Identification and some properties of a new fast-acting plasmin inhibitor in human plasma. Eur. J. Biochem. 69, 209–216.

    Article  PubMed  CAS  Google Scholar 

  • Conway, E. J. 1943. The chemical evolution of the ocean. Proc. Roy. Ir. Acad. 48B, 161.

    Google Scholar 

  • Conway, E. J. 1957. Micro-diffusion analysis and volumetric error. Crosby Lockwood, London, 4th edit.

    Google Scholar 

  • Conway, E. J., O’Connor, J. M. and O’Donovan, D. K. 1937. The influence of temperature on the activity of the kidney in relation to its influence on oxygen consumption. Proc. Roy. Ir. Acad. 44B, 1.

    Google Scholar 

  • Conway, E. J., Fitzgerald, O. and McDougald, R. C. 1946. Potassium accumulation in the proximal tubule of the frog’s kidney. J. Gen. Physiol. 29, 305.

    Article  CAS  Google Scholar 

  • Flute, P. T. 1977. Disorders of plasma fibrinogen sylnthesis. Brit. med. Bull. 33, 253–259.

    PubMed  CAS  Google Scholar 

  • Gaffney, P. J. 1973. The molecular and functional condition of plasma fibrinogen during thrombolytic therapy with streptokinase (SK). Thrombos. Res. 2, 105–114.

    Article  Google Scholar 

  • Gaffney, P. J. 1975. Distinction between fibrinogen and fibrin degradation products in plasma. Clin. Chim. Acta 65, 109–115.

    Article  PubMed  CAS  Google Scholar 

  • Gaffney, P. J. 1977. Structure of fibrinogen and degradation products of fibrinogen and fibrin. Brit. med. Bull. 33, 245–252.

    PubMed  CAS  Google Scholar 

  • Gaffney, P. J. 1981. The fibrinolytic system. In: Haemostasis and Thrombosis. Eds. A. L. Bloom and D. P. Thomas. Churchill Livingstone, Edinburgh, pp. 198–224.

    Google Scholar 

  • Gaffney, P. J. 1983. The occurrence and clinical relevance of fibrin fragments in blood. Ann N.Y. Acad. Sci. 408, 407–423.

    Article  PubMed  CAS  Google Scholar 

  • Gaffney, P. J., Chesterman, C. N. and Allington, M. J. 1974. Plasma fibrinogen and its fragments during streptokinase treatment. Brit. J. Haematol. 26, 285–293.

    Article  CAS  Google Scholar 

  • Gaffney, P. J. and Dobos, P. 1971. A structural aspect of human fibrinogen suggested by its plasmin degradation. FEBS Lett. 15, 13–16.

    Article  PubMed  CAS  Google Scholar 

  • Gaffney, P. J. and Whitaker, A. N. 1979. Fibrin crosslinks and lysis rates. Thrombos. Res. 14, 85–94.

    Article  CAS  Google Scholar 

  • Graeff, H. and Hafter, R. 1982. Detection and relevance of crosslinked fibrin derivatives in blood. Sem. Thrombos. Haemos. 8, 57–68.

    Article  CAS  Google Scholar 

  • Holt, J., Mahmoud, M. and Gaffney, P. J. 1979. The ability of fibrinogen and its degradation products to support ADP-induced platelet aggregation. Thrombos. Res. 16, 427–435.

    Article  CAS  Google Scholar 

  • Iwanaga, S., Suzuki, K. and Hashimoto, S. 1978. Bovine plasma cold-insoluble globulin. Gross structure and function. Ann. N.Y. Acad. Sci. 312, 56–73.

    Article  PubMed  CAS  Google Scholar 

  • Lijnen, H. R., Hoykaertsm, N. and Collen, D. 1980. Isolation and characterisation of a human plasma protein with affinity for the lysine-binding sites in plasminogen. Role in the regulation of fibrinolysis and identification as histidine-rich glycoprotein. J. Biol. Chem. 255, 10214–10222.

    PubMed  CAS  Google Scholar 

  • Marder, V. J. and Shulman, N. R. 1969. High molecular weight plasma derivatives of human fibrinogen produced by plasmin. II: Mechanism of their anticoagulant activity. J. Biol. Chem. 244, 2120–2124.

    PubMed  CAS  Google Scholar 

  • Menaché, D. 1983. Congenital fibrinogen abnormalities. Ann. N.Y. Acad. Sci. 408, 121–130.

    Article  PubMed  Google Scholar 

  • Mosher, D. 1975. Crosslinking of cold-insoluble globulin by fibrin stabilising factors. J. Biol. Chem. 250, 6614–6621.

    PubMed  CAS  Google Scholar 

  • Mullertz, S. and Clemmensen, I. 1976. The primary inhibitor of plasmin in blood. Biochemical J. 159, 545–553.

    CAS  Google Scholar 

  • Olexa, S. A. and Budzynski, A. Z. 1980. Effects of fibrinopeptide cleavage on the plasmic degradation pathways of human cross-linked fibrin. Biochemistry 19, 647–651.

    Article  PubMed  CAS  Google Scholar 

  • Pauling, L., Itano, H. A., Singer, S. J. and Wells, I. C. 1949. Sickle-cell anaemia, a molecular disease. Science 110, 543.

    Article  PubMed  CAS  Google Scholar 

  • Rickli, E. E. 1975. The activation mechanism of human plasminogen. Throm. Diath. Haemorr. 34, 386–395.

    CAS  Google Scholar 

  • Sakata, Y. and Aoki, N. 1980. Crosslinking of α2 plasmin inhibitor to fibrin by fibrin-stabilising factor. J. Clin. Invest. 65, 290–297.

    Article  PubMed  CAS  Google Scholar 

  • Saldeen, T. 1983. Vasoactive peptides derived from degradation of fibrinogen and fibrin. In: Molecular Biology of Fibrinogen and Fibrin. Eds. M. W. Mosesson and R. F. Doolittle. Ann. N.Y. Acad. Sci., New Yirk, 408 424–437.

    Google Scholar 

  • Tamaki, T. and Aoki, N. 1982. Crosslinking of α2- plasmin inhibitor to fibrin catalysed by activated stabilising factor. J. Biol. Chem. 257, 14767- 14772.

    PubMed  CAS  Google Scholar 

  • Whitaker, A. N., Rowe, E. A., Masci, P. and Gaffney, P. J. 1980. Identification of D dimer-E complex in disseminated intravascular coagulation (DIC). Throm. Res. 18, 453–459.

    Article  CAS  Google Scholar 

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  1. National Institute for Biological Standards and Control, Holly Hill, Hampstead, NW3 6RB, London, UK

    Patrick J. Gaffney

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  1. Patrick J. Gaffney
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Gaffney, P.J. Some aspects of the molecular pathology of thrombosis and haemorrhage. I.J.M.S. 153, 2–10 (1984). https://doi.org/10.1007/BF02940516

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