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Cyclosporine resistant effector cells in rabbit skin allografts

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Summary

Histoincompatible skin grafts in rabbits treated with cyclosporine can permanently engraft but show a transient mononuclear cellular infiltrate. This transient cyclosporine-resistant infiltrate consists of cells which are sensitive to steroids, radiation and cryopreservation. They have the same ACM-1 phenotype and the same characteristics as cyclosporine-sensitive cells.

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Authors and Affiliations

  1. Division of Hematology, Department of Research, Kantonsspital, CH-4031, Basel, Switzerland

    A. Gratwohl, I. Riederer, K. Walstra, H. Baldomero & B. Speck

Authors
  1. A. Gratwohl
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  2. I. Riederer
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  3. K. Walstra
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  4. H. Baldomero
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  5. B. Speck
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Additional information

9 January 1987

Supported by the Swiss National Research Foundation, Grant No. 3.908-0.83.

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Gratwohl, A., Riederer, I., Walstra, K. et al. Cyclosporine resistant effector cells in rabbit skin allografts. Experientia 43, 910–912 (1987). https://doi.org/10.1007/BF01951663

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  • DOI: https://doi.org/10.1007/BF01951663

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