Summary
After intravenous injection of l-14C-palmitic, acid, labeled fatty acids were found in the feces of 5 persons with steatorrhea of various origin. 2 patients with decompensated protein-losing enteropathy excreted 2.8 resp. 3.7% of the injected dose within 5 days, whereas in 3 others the loss was approx. 0.85% each.
Zusammenfassung
Nach intravenöser Verabreichung von l-14C-Palmitinsäure werden bei 5 Patienten mit Steatorrhoe unterschiedlicher Genese markierte Fettsäuren im Stuhl nachgewiesen. Gegenüber den einheitlich niedrigen Werten der übrigen Probanden scheiden 2 Patienten mit dekompensierter exsudativer Enteropathie relativ höhere Aktivitäten aus.
Literatur
Annegers, J. H.: Function of pancreatic juice and bile in assimilation of dietary triglyceride. Arch. intern. Med.93, 9 (1954).
Holasek, A.: Über den Ursprung des Kotfettes. Hoppe-Seylers Z. physiol. Chem.298, 224 (1954).
Jiminez-Diaz, C., Marina, C., Romeo, J. M., Perez Gomez, A.: Consideraciones sobre la significacion y naturaleza del esprue. Rec. clin. esp.37, 9 (1950).
—— Linazasoro, J. M., Marina, C., Romeo, J. M.: Studies on idiopathic steatorrhea with fat labeled (J131). Gastroenterologia (Basel)93, 228 (1960).
Kamer, J. H. v. d., t. Bokkel Huninink, H., Weyers, H. A.: Rapid method for the determination of fat in feces. J. biol. Chem.177, 347 (1949).
Lewis, G. T., Partin, H. C.: Fecal fat on an essential fat free diet. J. Lab. clin. Med.44, 91 (1954).
Mistilis, S. P., Skyring, A. P., Stephen, D. D.: Intestinal lymphangiectasia. Mechanism of enteric loss of plasma-protein and fat. Lancet1969 I, 77.
Pessoa, V. G., Kim, K. S., Ivy, A. C.: Fat absorption in absence of bile and pancreatic juice. Amer. J. Physiol.174, 209 (1953).
Mahin, D. T., Lofberg, R. T.: A simplified method of sample preparation for determination of tritium, carbon — 14, or sulfat — 35 in blood or tissue by liquid scintillation counting. Analyt. Biochem.16, 500 (1966).
Webb, J. P. W., James, A. T., Kellock, T. D.: Digestion, Absorption intestinale et Transport des Glycerides chez les Animaux Supérieurs, p. 113. Paris: Ed. Centre Nat. Recherche Scient. 1961.
—— —— —— The influence of diet on the quality of faecal fat in patients with and without steatorrhoea. Gut4, 37 (1963).
Wiggins, H. A., Howell, K. E., Kellock, T. D., Stalder, J.: The origin of faecal fat. Gut10, 400 (1969).
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
Begemann, F. Gastrointestinaler Verlust endogener Fettsäuren bei Steatorrhoen verschiedener Genese. Klin Wochenschr 49, 110–111 (1971). https://doi.org/10.1007/BF01497310
Received:
Issue Date:
DOI: https://doi.org/10.1007/BF01497310