SpringerLink
Log in

Prognostic factors in oligodendrogliomas

  • Clinical Articles
  • Published:
Acta Neurochirurgica Aims and scope Submit manuscript

Summary

An outcome analysis was performed on 96 patients with pure cerebral oligodendrogliomas operated in the 30-year period 1962 to 1991.

The most important predictive prognostic factors were youth and no neurological deficit, demonstrated as a median survival for the group younger than 20 years of 17.5 years and for the group older than 60 years of 13 months. The group without neurological deficits had a 5-years survival of 43 per cent while the group with deficits had a 5-years survival of 5 per cent.

The 5-years survival for oligodendroglioma of grade II was 46 per cent and for grade III 10 per cent.

We found no effect of radiotherapy on survival, neither in the whole material or in any subgroup.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Subscribe and save

Springer+ Basic
EUR 32.99 /Month
  • Get 10 units per month
  • Download Article/Chapter or Ebook
  • 1 Unit = 1 Article or 1 Chapter
  • Cancel anytime
Subscribe now

Buy Now

Price includes VAT (Spain)

Instant access to the full article PDF.

Institutional subscriptions

Similar content being viewed by others

References

  1. Bullard DE (1995) Surgical aspects and general management of oligodendrogliomas. In: Apuzzo MLJ (ed) Benign cerebral glioma. American Association of Neurological Surgeons, Illinois, pp 397–412

    Google Scholar 

  2. Bullard DE, Rawlings CE, Phillips B, Cox EB, Schold SC, Burger P, Harlerin EC (1987) Oligodendroglioma. An analysis of the value of radiation therapy. Cancer 60: 2179–2188

    PubMed  Google Scholar 

  3. Celli P, Nofrone I, Palma L, Cantore G, Fortuna A (1994) Cerebral Oligodendroglioma: prognostic factors and life history. Neurosurgery 35(6): 1018–1035

    PubMed  Google Scholar 

  4. Chin HW, Hazel JJ, Kim TH, Webster JH (1980) Oligodendrogliomas I. A clinical study of cerebral oligodendrogliomas. Cancer 45: 1458–1466

    PubMed  Google Scholar 

  5. Kros JM, Troost D, Van Eden CG, Van der Werf AJ, Uylings HB (1988) Oligodendroglioma. A comparison of two grading systems. Cancer 61: 2251–2259

    PubMed  Google Scholar 

  6. Lindegaard KF, Mørk SJ, Eide GE, Halvorsen TB, Hatlevoll R, Solgaard T, Dahl O, Ganz J (1987) Statistical analysis of clinicopathological features, radiotherapy and survival in 170 cases of Oligodendroglioma. J Neurosurg 67: 224–230

    PubMed  Google Scholar 

  7. Ludwig CL, Smith MT, Godfrey AD, Armbrustmacher VW (1986) A clinicopathological study of 323 patients with oligodendrogliomas. Ann Neurol 19: 15–21

    PubMed  Google Scholar 

  8. Muller W, Afra D, Schröder R (1977) Supratentorial recurrences of gliomas. Morphological studies in relation to time intervals with oligodendrogliomas. Acta Neurochir (Wien) 39: 15–25

    Google Scholar 

  9. Mørk SJ, Lindegaard KF, Halvorsen TB, Lehmann EH, Solgaard T, Hatlevoll R, Harvei S, Ganz J (1985) Oligodendroglioma: Incidence and biological behaviour in a defined population. J Neurosurg 63: 881–889

    PubMed  Google Scholar 

  10. Neumann J, Kimpel J, Gulotta F (1978) Das Oligodendrogliom. Der klinische Verlauf in Bezug zum histologischen Grading. Neurochir 21: 35–42

    Google Scholar 

  11. Nijjar TS, Simpson WJ, Gadalla T, Math M, McCartney M (1993) Oligodendroglioma. The Princess Margaret Hospital Experience (1958–1984). Cancer 71: 4002–4006

    PubMed  Google Scholar 

  12. Reedy DP, Bay JW, Hahn JF (1983) Role of radiation therapy in the treatment of cerebral Oligodendroglioma: an analysis of 57 cases and a literature review. Neurosurgery 13: 499–503

    PubMed  Google Scholar 

  13. Roberts M, German WJ (1966) A long term study of patients with oligodendrogliomas. J Neurosurg 24: 697–700

    PubMed  Google Scholar 

  14. Russel DS, Rubinstein LJ (1989) Pathology of tumours of the nervous system, 5th Ed. Edward Arnold, London.

    Google Scholar 

  15. Shaw EG, Scheithauer BW, O'Fallon JR, Tazelaar HD, Davis DH (1992) Oligodendrogliomas: The Mayo Clinic experience. J Neurosurg 76: 428–434

    PubMed  Google Scholar 

  16. Sheline GE, Boldrey E, Karlsberg P, Phillips TL (1964) Therapeutic considerations in tumours affecting the central nervous system: Oligodendrogliomas. Radiology 82: 84–89

    PubMed  Google Scholar 

  17. Shimizu KT, Tran LM, Mark RJ, Selch MT (1993) Management of oligodendrogliomas. Radiology 186: 569–572

    PubMed  Google Scholar 

  18. SOLO Survival Analysis (computer program) (1989) BMPD Statistical Software. Los Angeles, CA

    Google Scholar 

  19. Sun ZM, Genka S, Shitara N, Akanuma A, Takakura K (1988) Factors possibly influencing the prognosis of oligodendroglioma. Neurosurgery 22(5): 886–891

    PubMed  Google Scholar 

  20. Wallner KE, Gonzales M, Sheline GE (1988) Treatment of oligodendrogliomas with or without postoperative irradiation. J Neurosurg 68(5): 684–688

    PubMed  Google Scholar 

  21. Weir B, Elvidge AR (1968) Oligodendrogliomas: an analysis of 63 cases. J Neurosurg 29: 500–505

    Google Scholar 

  22. WHO International Histological classification of tumours. In: Kleinhues P, Burger PC, Scheithauer BW (eds) Histological ty** of tumours of the central nervous system. 2nd Ed. Springer, Berlin Heidelberg New York Tokyo

  23. Wilkinsom IM, Anderson JR, Holmes AE (1987) Oligodendroglioma: An analysis of 42 cases. J Neurol Neurosurg Psychiatry 50: 304–312

    PubMed  Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Rigshospitalet, University Clinic of Neurosurgery, Copenhagen

    L. Westergaard M. D. & F. Gjerris

  2. Institute of Neuropathology, University of Copenhagen, Denmark

    L. Klinken

Authors
  1. L. Westergaard M. D.
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. F. Gjerris
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. L. Klinken
    View author publications

    You can also search for this author in PubMed Google Scholar

Rights and permissions

Reprints and permissions

About this article

Cite this article

Westergaard, L., Gjerris, F. & Klinken, L. Prognostic factors in oligodendrogliomas. Acta neurochir 139, 600–605 (1997). https://doi.org/10.1007/BF01411993

Download citation

  • Issue Date:

  • DOI: https://doi.org/10.1007/BF01411993

Keywords

Search

Navigation