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Characterization of recent influenza a variants

I. Biochemical studies

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Summary

The thermal stability and resistance against proteolysis and reducing agents has been compared for the hemagglutinin and neuraminidase of four influenza A2 strains.

The recent A2/England/72 isolate was found to differ significantly from the parent A2/Hong Kong/68 strain. The A2/England/69 variant was, on the other hand, indistinguishable from the Hong Kong virus.

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References

  1. Bachmayer, H., andG. Schmidt: Selective Removal of Neuraminidase from Influenza A2 Viruses. Med. Microbiol. Immunol.158, 91–94 (1972).

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  2. Pereira, M. S., andG. C. Schild: An antigenic variant of the HongKong/68 influenza A2 virus. J. Hyg. (Lond.)69, 99–103 (1971).

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  3. Schmidt, G., K.Wagner, and H.Bachmayer: Unpublished experiments (1973).

  4. Antigenic Variation in influenza A viruses. WHO Wkly epidem. Rec.47, 381–384 (1972).

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Author notes

  1. H. Bachmayer

    Present address: Sandoz Forschungsinstitut, Wien, Austria

Authors and Affiliations

  1. Sandoz Forschungsinstitut, Wien, Austria

    K. Wagner

Authors
  1. H. Bachmayer
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  2. K. Wagner
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Bachmayer, H., Wagner, K. Characterization of recent influenza a variants. Archiv f Virusforschung 42, 177–181 (1973). https://doi.org/10.1007/BF01270838

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  • DOI: https://doi.org/10.1007/BF01270838

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