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Über die Bedeutung der Schilddrüse für die stoffwechselsteigernde Wirkung von Amphetamin

The role of the thyroid gland in the calorigenic action of amphetamine

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Summary

The rate of oxygen consumption and carbon dioxide production was measured in rats following the injection of amphetamine. Amphetamine is strongly calorigenic in normal as well as in triiodothyronine treated thyroidectomized animals. In hypothyroid thyroidectomized animals amphetamine causes only a very small increase in oxygen consumption.

Zusammenfassung

Messungen des Sauerstoffverbrauchs und der Kohlendioxidproduktion ergaben, daß Amphetamin auch bei schilddrüsenlosen Ratten calorigen wirkt, wenn der bei diesen Tieren bestehende Hormonmangel durch Zufuhr von Trijodthyronin ausgeglichen wird.

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Authors and Affiliations

  1. Pharmakologisches Institut der Universität Münster i. W., Germany

    Hsi Chu, K. Opitz & E. Intemann

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  1. Hsi Chu
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  2. K. Opitz
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  3. E. Intemann
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Chu, H., Opitz, K. & Intemann, E. Über die Bedeutung der Schilddrüse für die stoffwechselsteigernde Wirkung von Amphetamin. Naunyn-Schmiedebergs Arch. Pharmak. u. Exp. Path. 263, 358–362 (1969). https://doi.org/10.1007/BF00537609

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  • DOI: https://doi.org/10.1007/BF00537609

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