Log in

Nitrogen metabolite repression of arginase, ornithine transaminase and allantoinase in a conditional ethionine-resistant mutant of Saccharomyces cerevisiae with low activity of catabolic NAD-specific glutamate dehydrogenase

  • Physiology and Growth
  • Published:
Antonie van Leeuwenhoek Aims and scope Submit manuscript

This is a preview of subscription content, log in via an institution to check access.

Access this article

Subscribe and save

Springer+ Basic
EUR 32.99 /Month
  • Get 10 units per month
  • Download Article/Chapter or Ebook
  • 1 Unit = 1 Article or 1 Chapter
  • Cancel anytime
Subscribe now

Buy Now

Price includes VAT (Canada)

Instant access to the full article PDF.

References

  • Béchet, J., Grenson, M. and Wiame, J. M. 1970. Mutations affecting the repressibility of arginine biosynthetic enzymes in Saccharomyces cerevisiae.— Eur. J. of Biochem. 12: 31–39.

    Google Scholar 

  • Bourgeois, C., 1969. Influence de la lysine sur la croissance de Saccharomyces cerevisiae.— Bull. Soc. Chim. Biol. 51: 935–949.

    Google Scholar 

  • Cherest, H., Surdin-Kerjan, Y., Exinger, F. and Lacroute, F., 1978. S-adenosyl methionine requiring mutants in Saccharomyces cerevisiae: Evidence for the existence of two methionine adenosyl transferase.— Mol. Gen. Genet. 163: 153–167.

    Google Scholar 

  • Cooper, T. G. and Lawther, R. P. 1973. Induction of the allantoin degradative enzymes in Saccharomyces cerevisiae by the last intermediate of the pathway.— Proc. Nat. Acad. Sci. USA 70: 2340–2344.

    Google Scholar 

  • Dubois, E. and Grenson, M. 1974. Absence of involvement of glutamine synthetase and of NAD-linked glutamate dehydrogenase in the nitrogen catabolite repression of arginase and other enzymes in Saccharomyces cerevisiae.— Biochem. Biophys. Res. Commun. 60: 150–157.

    Google Scholar 

  • Dubois, E., Grenson, M. and Wiame, J. M., 1973. Release of the ammonia effect on three catabolic enzymes by NADP-specific glutamate dehydrogenase-less mutations in Saccharomyces cerevisiae. — Biochem. Biophys. Res. Commun. 50: 962–972.

    Google Scholar 

  • Dubois, E., Grenson, M. and Wiame, J. M. 1974. The participation of the anabolic glutamate dehydrogenase in the nitrogen catabolite repression of arginase in Saccharomyces cerevisiae.—Eur. J. Biochem. 48: 603–616.

    Google Scholar 

  • Dubois, E., Vissers, S., Grenson, M. and Wiame, J. M. 1977. Glutamine and ammonia in nitrogen catabolite repression of Saccharomyces cerevisiae.— Biochem. Biophys. Res. Commun. 75: 233–239.

    Google Scholar 

  • Dubois, E. and Wiame, J. M. 1976. Non specific induction of arginase in Saccharomyces cerevisiae. — Biochimie 58: 207–211.

    Google Scholar 

  • Gits, J. J. and Grenson, M. 1967. Multiplicity of the amino acid permeases in Saccharomyces cerevisiae. III. Evidence for a specific methionine-transporting system.— Biochim. Biophys. Acta 135: 507–516.

    Google Scholar 

  • Grenson, M. and Hennaut, C. 1971. Mutation affecting activity of several distinct amino acid transport systems in Saccharomyces cerevisiae.— J. of Bacteriol. 105: 477–482.

    Google Scholar 

  • Grenson, M. and Hou, C. 1972. Ammonia inhibition of the general amino acid permease and its suppression in NADPH-specific glutamate dehydrogenaseless mutants of Saccharomyces cerevisiae. — Biochem. Biophys. Res. Commun. 48: 749–756.

    Google Scholar 

  • Grenson, M., Hou, C. and Crabeel, M. 1970. Multiplicity of the amino acid permeases in Saccharomyces cerevisiae. J. Bacteriol. 103: 770–777.

    Google Scholar 

  • Johnston, J. R. and Mortimer, R. K. 1959. Use of snail digestive juice in isolation of yeast spore tetrads.— J. Bacteriol. 78: 292.

    Google Scholar 

  • McClary, D. O., Nulty, W. T. and Miller, G. R. 1959. Effect of potassium versus sodium in the sporulation of Saccharomyces cerevisiae.— J. Bacteriol. 78: 362–368.

    Google Scholar 

  • Middelhoven, W. J. 1964. The pathway of arginine breakdown in Saccharomyces cerevisiae.—Biochim. Biophys. Acta 93: 650–652.

    Google Scholar 

  • Middelhoven, W. J. 1977. Isolation and characterization of methylammonium-resistant mutants of Saccharomyces cerevisiae with relieved nitrogen metabolite repression of allantoinase, arginase and ornithine transaminase synthesis.— J. Gen. Microbiol. 100: 257–269.

    Google Scholar 

  • Middelhoven, W. J., Anderegg, M. J. P. T., Meijs, A. W. H. M. and van Egmond, H. P. 1976. The substrate constant for the ammonium ion of growing Saccharomyces cerevisiae.— Antonie van Leeuwenhoek 42: 293–297.

    Google Scholar 

  • Middelhoven, W. J. and Arkesteyn, G. J. M. W. 1981. Induction and derepression of arginase and ornithine transaminase in different strains of Saccharomyces cerevisiae.— Antonie van Leeuwenhoek 47: 121–131.

    Google Scholar 

  • Middelhoven, W. J., van Eijk, J., van Renesse, R. and Blijham, J. M. 1978. A mutant of Saccharomyces cerevisiae lacking catabolic NAD-specific glutamate dehydrogenase. Growth characteristics of the mutant and regulation of enzyme synthesis in the wild-type strain.— Antonie van Leeuwenhoek 44: 311–320.

    Google Scholar 

  • Middelhoven, W. J. and Hoogkamer-te Niet, M. C. 1981. Repression of catabolic NAD-specific glutamate dehydrogenase of Saccharomyces cerevisiae by arginine, allantoin and urea.— FEMS Microbiol. Lett. 10: 307–311.

    Google Scholar 

  • Roon, R. J. and Even, H. L. 1973. Regulation of nicotinamide adenine dinucleotide and nicotinamide adenine dinucleotide phosphate-dependent glutamate dehydrogenases of Saccharomyces cerevisiae.— J. Bacteriol. 116: 367–372.

    Google Scholar 

  • Sumrada, R. and Cooper, T. G. 1978. Basic amino acid inhibition of cell division and macromolecular synthesis in Saccharomyces cerevisiae.— J. Gen. Microbiol. 108: 45–56.

    Google Scholar 

  • Surdin, Y., Sly, W., Sire, J., Bordes, A. M. and de Robichon-Szulmajster, H. 1965. Propriétés et contrôle génétique du systéme d'accumulation des acides aminés chez Saccharomyces cerevisiae. — Biochim. Biophys. Acta 107: 546–566.

    Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Rights and permissions

Reprints and permissions

About this article

Cite this article

Middelhoven, W.J., Hoogkamer-te Niet, M.C. Nitrogen metabolite repression of arginase, ornithine transaminase and allantoinase in a conditional ethionine-resistant mutant of Saccharomyces cerevisiae with low activity of catabolic NAD-specific glutamate dehydrogenase. Antonie van Leeuwenhoek 48, 417–432 (1982). https://doi.org/10.1007/BF00448414

Download citation

  • Received:

  • Issue Date:

  • DOI: https://doi.org/10.1007/BF00448414

Keywords

Navigation