Summary
The clinical and neurological features of four siblings (2 ♂, 2 ♀) affected by syringomyelia are described. A fifth sister was affected by an acoustic neurinoma. Since neither parent showed signs of syringomyelia, this is considered to be a datum substantiating the dysembryogenetic theory of the syringomyelia syndrome.
Zusammenfassung
Die klinisch-neurologischen Befunde von 4 Geschwistern (2 ♂, 2 ♀) mit Syringomyelie werden beschrieben. Eine 5. Schwester hatte ein Akustikneuronom. Beide Eltern zeigten keine Zeichen von Syringomyelie. Das familiäre Vorkommen wird als Stütze für die dysembryogenetische Theorie angesehen.
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We are grateful to Dr. M. Savoiardo for his many suggestions and for his interpretation of radiological features. We should like to thank Dr. L. De Lorenzi for allowing us to publish details about patients.
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Caraceni, T., Giovannini, P. Familial syringomyelia. Arch. Psychiat. Nervenkr. 224, 331–340 (1977). https://doi.org/10.1007/BF00341615
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DOI: https://doi.org/10.1007/BF00341615